Skip to main content
SpringerLink
Log in

The good company of T-type calcium channels

Commentary on: “T-type calcium channelosome,” a review by N. Weiss and G. W. Zamponi

  • Commentary
  • Published:
Pflügers Archiv - European Journal of Physiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Data availability

No datasets were generated or analysed during the current study.

References

  1. Campiglio M, Flucher BE (2015) The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels. J Cell Physiol 230:2019–2031. https://doi.org/10.1002/jcp.24998

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Catterall WA (2023) Voltage gated sodium and calcium channels: discovery, structure, function, and Pharmacology. Channels (Austin) 17:2281714. https://doi.org/10.1080/19336950.2023.2281714

    Article  PubMed  Google Scholar 

  3. Garcia-Caballero A, Gadotti VM, Stemkowski P, Weiss N, Souza IA, Hodgkinson V, Bladen C, Chen L, Hamid J, Pizzoccaro A, Deage M, Francois A, Bourinet E, Zamponi GW (2014) The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity. Neuron 83:1144–1158. https://doi.org/10.1016/j.neuron.2014.07.036

    Article  CAS  PubMed  Google Scholar 

  4. Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen BX, Kushnir A, Dangas K, Gygi SP, Pitt GS, Colecraft HM, Ben-Johny M, Kalocsay M, Marx SO (2020) Mechanism of adrenergic Ca(V)1.2 stimulation revealed by proximity proteomics. Nature 577:695–700. https://doi.org/10.1038/s41586-020-1947-z

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Lory P, Nicole S, Monteil A (2020) Neuronal Cav3 channelopathies: recent progress and perspectives. Pflugers Arch 472:831–844. https://doi.org/10.1007/s00424-020-02429-7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Mezghrani A, Monteil A, Watschinger K, Sinnegger-Brauns MJ, Barrere C, Bourinet E, Nargeot J, Striessnig J, Lory P (2008) A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels. J Neurosci 28:4501–4511. https://doi.org/10.1523/JNEUROSCI.2844-07.2008

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Monteil A, Chausson P, Boutourlinsky K, Mezghrani A, Huc-Brandt S, Blesneac I, Bidaud I, Lemmers C, Leresche N, Lambert RC, Lory P (2015) Inhibition of Cav3.2 T-type calcium channels by Its Intracellular I-II Loop. J Biol Chem 290:16168–16176. https://doi.org/10.1074/jbc.M114.634261

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Monteil A, Guerineau NC, Gil-Nagel A, Parra-Diaz P, Lory P, Senatore A (2024) New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN. Physiol Rev 104:399–472. https://doi.org/10.1152/physrev.00014.2022

    Article  PubMed  Google Scholar 

  9. Muller CS, Haupt A, Bildl W, Schindler J, Knaus HG, Meissner M, Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U (2010) Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci U S A 107:14950–14957. https://doi.org/10.1073/pnas.1005940107

    Article  PubMed  PubMed Central  Google Scholar 

  10. Weiss N, Zamponi GW T-type calcium channelosome. Pflugers Arch

Download references

Author information

Authors and Affiliations

  1. IGF, Univ Montpellier, CNRS, INSERM, Montpellier, France

    Philippe Lory

  2. LabEx ‘Ion Channel Science and Therapeutics’, Montpellier, France

    Philippe Lory

  3. Institut de Génomique Fonctionnelle – CNRS, 141 rue de la Cardonille, 34094, Montpellier, France

    Philippe Lory

Authors
  1. Philippe Lory
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

PL is the single author of the commentary.

Corresponding author

Correspondence to Philippe Lory.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lory, P. The good company of T-type calcium channels. Pflugers Arch - Eur J Physiol 476, 149–150 (2024). https://doi.org/10.1007/s00424-023-02903-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00424-023-02903-y

Search

Navigation