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Auxiliary liver transplantation in acute liver failure in the rat – an illustrated description of a new surgical approach

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Abstract

Introduction: To investigate auxiliary liver transplantation successfully in rats suffering from acute liver failure, we developed a new surgical approach. Methods: A 70% hepatectomized liver graft was implanted into the right upper quadrant of the abdomen. The donor portal vein was anastomosed with the recipient's right renal artery using the splint technique. The donor infrahepatic vena cava was attached onto the recipient vena cava end to side. The bile duct was implanted into the duodenum.

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Authors and Affiliations

  1. Department of General Surgery, University Clinic, University of Cologne, Germany, , , , , , DE

    Karina Schleimer

  2. Department of General Surgery, University Clinic, University of Essen, Germany, , , , , , DE

    Reinhard Lange

  3. Institute of Physiological Chemistry, University Clinic, University of Essen, Germany, , , , , , DE

    Ursula Rauen

  4. Department of General Surgery, St. Barbara-Hospital Gladbeck, Barbarastr. 1, D-45964 Gladbeck, Germany (Tel.: +49-2043-278-5400, Fax: +49-2043-278-5409), , , , , , DE

    J. Erhard

Authors
  1. Karina Schleimer
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  2. Reinhard Lange
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  3. Ursula Rauen
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  4. J. Erhard
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Received: 20 March 1998; in revised form: 14 September 1998 Accepted: 13 October 1998

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Schleimer, K., Lange, R., Rauen, U. et al. Auxiliary liver transplantation in acute liver failure in the rat – an illustrated description of a new surgical approach. Langenbeck's Arch Surg 384, 204–208 (1999). https://doi.org/10.1007/s004230050193

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  • DOI: https://doi.org/10.1007/s004230050193

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