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Effects of different preoperative enteral nutrition feeding routes on the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula

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Abstract

Purpose

The purpose of this study is to investigate the effects of different preoperative enteral nutrition feeding routes on the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula.

Methods

From January 2015 to June 2019, patients with small intestinal fistula and receiving a definitive surgery were enrolled. According to the feeding route, patients were divided into a nasointestinal tube group and a nasogastric tube group. Clinical characteristics of the two groups were analyzed, and the influence of the two route on the recovery of gastrointestinal function was evaluated.

Result

A total of 151 patients were enrolled in our study. There were 49 patients in the nasogastric tube group, and 102 patients in the nasointestinal tube group. Enteral nutrition via nasogastric feeding route had a positive effect on shortening the duration of gastrointestinal decompression (adjusted HR = 2.488, 95% CI: 1.692–3.659, P < 0.001). After propensity matching (PM), 44 patients were enrolled (22 vs 22). EN via nasogastric tube was a positive factor for getting rid of gastrointestinal decompression (adjusted HR = 3.563, 95% CI: 1.639–7.746, P = 0.001).

Conclusion

Preoperative enteral nutrition via nasogastric route can reduce the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula.

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Authors and Affiliations

  1. Department of General Surgery, Jiangning Hospital, Nanjing, Jiangsu, China

    Xin Xu, Lina Cai, Zheng Yao, Risheng Zhao & Yunzhao Zhao

  2. Department of General Surgery, Jinling Hospital, Nanjing, Jiangsu, China

    Weiliang Tian & Yunzhao Zhao

  3. Department of Enterocutaneous Fistula Surgery, Jiangning Hospital, Hushan Road No. 169, Nanjing, Jiangsu, China

    Zheng Yao & Risheng Zhao

Authors
  1. Xin Xu
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  2. Lina Cai
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  3. Weiliang Tian
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  4. Zheng Yao
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  5. Risheng Zhao
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  6. Yunzhao Zhao
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Contributions

Yunzhao Zhao, Risheng Zhao, and Weiliang Tian provide research objects. Xin Xu and Risheng Zhao collected and analyzed the data. Zheng Yao, Xin Xu, and Weiliang Tian wrote the main manuscript text. Xin Xu prepared the figures. Lina Cai revised the manuscript. Zheng Yao designed the research. Xin Xu and Lina Cai were the first authors. Zheng Yao and Risheng Zhao were the correspondence authors.

Corresponding authors

Correspondence to Zheng Yao or Risheng Zhao.

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Ethical approval

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all the individual participants included in the study.

Research data for this article

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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The authors declare that they have no conflict of interest.

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Xu, X., Cai, L., Tian, W. et al. Effects of different preoperative enteral nutrition feeding routes on the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula. Langenbecks Arch Surg 406, 2837–2848 (2021). https://doi.org/10.1007/s00423-021-02301-x

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  • DOI: https://doi.org/10.1007/s00423-021-02301-x

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