Skip to main content
Log in

Laparoscopic adrenalectomy—10-year experience at a teaching hospital

  • Original Article
  • Published:
Langenbeck's Archives of Surgery Aims and scope Submit manuscript

Abstract

Background

Minimally invasive adrenalectomy has been adopted as the treatment of choice for benign adrenal tumors. This study aimed to investigate the outcome of laparoscopic adrenalectomies performed over a 10-year period at a teaching hospital.

Methods

All laparoscopic adrenalectomies carried out between 1 April 2000 and 31 March 2010 were evaluated with respect to perioperative management, complications, conversion rate, learning curve, tumor size, and surgically relevant characteristics of different adrenal pathologies.

Results

Over a period of 10 years, 215 laparoscopic lateral transabdominal adrenalectomies were carried out for Conn’s syndrome (n = 90), Cushing’s syndrome (n = 72), pheochromocytoma (n = 30), metastatic disease (n = 8), incidentalomas (n = 10), and other rare adrenal pathologies (n = 5). Morbidity, mortality, and conversion rate were 7.0, 0.9, and 4.2 %, respectively. Patients with Cushing’s disease and bilateral adrenalectomy showed a higher complication rate. In retrospect, the indication for a laparoscopic approach was at least questionable in five cases. During these 10 years, four surgeons unfamiliar with the technique received intensive training to a defined plan.

Conclusions

Laparoscopic adrenalectomy represents a safe operating technique associated with few complications and a low conversion rate. Patients with severe Cushing’s disease are prone to complications and require intensive monitoring postoperatively. Laparoscopic adrenalectomy is associated with a learning curve, and particular emphasis should be given to surgical training.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Thompson GB, Grant CS, van Heerden JA, Schlinkert RT, Young WF Jr, Farley DR, Ilstrup DM (1997) Laparoscopic versus open posterior adrenalectomy: a case-control study of 100 patients. Surgery 122:1132–1136

    Article  CAS  PubMed  Google Scholar 

  2. Barreca M, Presenti L, Renzi C, Cavallaro G, Borrelli A, Stipa F, Valeri A (2003) Expectations and outcomes when moving from open to laparoscopic adrenalectomy: multivariate analysis. World J Surg 27:223–228

    PubMed  Google Scholar 

  3. Gumbs AA, Gagner M (2006) Laparoscopic adrenalectomy. Best Pract Res Clin Endocrinol Metab 20:483–499

    Article  PubMed  Google Scholar 

  4. Assalia A, Gagner M (2004) Laparoscopic adrenalectomy. Br J Surg 91:1259–1274

    Article  CAS  PubMed  Google Scholar 

  5. Walz MK, Alesina PF, Wenger FA, Deligiannis A, Szuczik E, Petersenn S, Ommer A, Groeben H, Peitgen K, Janssen OE, Philipp T, Neumann HP, Schmid KW, Mann K (2006) Posterior retroperitoneoscopic adrenalectomy—results of 560 procedures in 520 patients. Surgery 140(6):943–948

    Article  PubMed  Google Scholar 

  6. Perrier ND, Kennamer DL, Bao R, Jimenez C, Grubbs EG, Lee JE, Evans DB (2008) Posterior retroperitoneoscopic adrenalectomy: preferred technique for removal of benign tumors and isolated metastases. Ann Surg 248:666–674

    PubMed  Google Scholar 

  7. Ramacciato G, Nigri GR, Petrucciani N, Di Santo V, Piccoli M, Buniva P, Valabrega S, D’Angelo F, Aurello P, Mercantini P, Del Gaudio M, Melotti G (2011) Minimally invasive adrenalectomy: a multicenter comparison of transperitoneal and retroperitoneal approaches. Am Surg 77:409–416

    PubMed  Google Scholar 

  8. Goitein D, Mintz Y, Gross D, Reissman P (2004) Laparoscopic adrenalectomy: ascending the learning curve. Surg Endosc 18:771–773

    Article  CAS  PubMed  Google Scholar 

  9. Barczynski M, Konturek A, Golkowski F, Cichon S, Huszno B, Peitgen K, Walz MK (2007) Posterior retroperitoneoscopic adrenalectomy: a comparison between the initial experience in the invention phase and introductory phase of the new surgical technique. World J Surg 31:65–71

    Article  PubMed  Google Scholar 

  10. Park HS, Roman SA, Sosa JA (2009) Outcomes from 3,144 adrenalectomies in the United States: which matters more, surgeon volume or specialty? Arch Surg 144:1060–1067

    Article  PubMed  Google Scholar 

  11. Castillo OA, Vitagliano G, Secin FP, Kerkebe M, Arellano L (2008) Laparoscopic adrenalectomy for adrenal masses: does size matter? Urology 71(6):1138–1141

    Article  PubMed  Google Scholar 

  12. Rosoff JS, Raman JD, Del Pizzo JJ (2008) Laparoscopic adrenalectomy for large adrenal masses. Curr Urol Rep 9(1):73–79

    Article  PubMed  Google Scholar 

  13. Ramacciato G, Mercantini P, La Torre M, Di Benedetto F, Ercolani G, Ravaioli M, Piccoli M, Melotti G (2008) Is laparoscopic adrenalectomy safe and effective for adrenal masses larger than 7 cm? Surg Endosc 22(2):516–521

    Article  PubMed  Google Scholar 

  14. Miller BS, Ammori JB, Gauger PG, Broome JT, Hammer GD, Doherty GM (2010) Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma. World J Surg 34:1380–1385

    Article  CAS  PubMed  Google Scholar 

  15. Leboulleux S, Deandreis D, Al Ghuzlan A, Auperin A, Goere D, Dromain C, Elias D, Caillou B, Travagli JP, De Baere T, Lumbroso J, Young J, Schlumberger M, Baudin E (2010) Adrenocortical carcinoma: is the surgical approach a risk factor of peritoneal carcinomatosis? Eur J Endocrinol 162:1147–1153

    Article  CAS  PubMed  Google Scholar 

  16. Porpiglia F, Miller BS, Manfredi M, Fiori C, Doherty GM (2011) A debate on laparoscopic versus open adrenalectomy for adrenocortical carcinoma. Horm Cancer 2:372–377

    Article  PubMed  Google Scholar 

  17. Brix D, Allolio B, Fenske W, Agha A, Dralle H, Jurowich C, Langer P, Mussack T, Nies C, Riedmiller H, Spahn M, Weismann D, Hahner S, Fassnacht M (2010) Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients. Eur Urol 58:609–615

    Article  PubMed  Google Scholar 

  18. Shen WT, Sturgeon C, Duh QY (2005) From incidentaloma to adrenocortical carcinoma: the surgical management of adrenal tumors. J Surg Oncol 89:186–192

    Article  PubMed  Google Scholar 

  19. Dindo D, Demartines N, Clavien P (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205e13

    Article  Google Scholar 

  20. Ali JM, Liau SS, Gunning K, Jah A, Huguet EL, Praseedom RK, Jamieson NV (2012) Laparoscopic adrenalectomy: auditing the 10 year experience of a single centre. Surgeon 10(5):267–272

    Article  PubMed  Google Scholar 

  21. Conzo G, Pasquali D, Della Pietra C, Napolitano S, Esposito D, Iorio S, DeBellis A, Docimo G, Ferraro F, Santini L, Sinisi A (2013) Laparoscopic adrenal surgery: ten-year experience in a single institution. BMC Surg 13(Suppl 2):S5

    Article  PubMed Central  PubMed  Google Scholar 

  22. Hallfeldt KK, Mussack T, Trupka A, Hohenbleicher F, Schmidbauer S (2003) Laparoscopic lateral adrenalectomy versus open posterior adrenalectomy for the treatment of benign adrenal tumors. Surg Endosc 17(2):264–267

    Article  CAS  PubMed  Google Scholar 

  23. Jager E, Heintz A, Junginger T (2004) Synchronous bilateral endoscopic adrenalectomy: experiences after 18 operations. Surg Endosc 18:314–318

    Article  CAS  PubMed  Google Scholar 

  24. Ku JH, Yeo WG, Kwon TG, Kim HH (2005) Laparoscopic adrenalectomy for functioning and nonfunctioning adrenal tumors: analysis of surgical aspects based on histological types. Int J Urol 12:1015–1021

    Article  PubMed  Google Scholar 

  25. Takata MC, Kebebew E, Clark OH, Duh QY (2008) Laparoscopic bilateral adrenalectomy: results for 30 consecutive cases. Surg Endosc 22(1):202–207

    Article  CAS  PubMed  Google Scholar 

  26. Henry JF, Defechereux T, Raffaelli M, Lubrano D, Gramatica L (2000) Complications of laparoscopic adrenalectomy: results of 169 consecutive procedures. World J Surg 24:1342–1346

    Article  CAS  PubMed  Google Scholar 

  27. David G, Mintz Y, Gross D, Reissman P (2004) Laparoscopic adrenalectomy: ascending the learning curve. Surg Endosc 18:771–773

    Article  PubMed  Google Scholar 

  28. Stefanidis D, Goldfarb M, Kercher KW, Hope WW, Richardson W, Fanelli RD (2013) SAGES guidelines for minimally invasive treatment of adrenal pathology. Surg Endosc 27:3960–3980

    Article  PubMed  Google Scholar 

  29. Turrentine FE, Henderson WG, Khuri SF, Schiffnet TL, Inabnet WB (2007) Adrenalectomy in Veterans Affairs and selected university medical centers: results of the patient safety in surgery study. J Am Coll Surg 204:1273–1293

    Article  PubMed  Google Scholar 

  30. Lombardi CP, Raffaelli M, Boniardi M, De Toma G, Marzano LA, Miccoli P, Minni F, Morino M, Pelizzo MR, Pietrabissa A, Renda A, Valeri A, De Crea C, Bellantone R (2012) Adrenocortical carcinoma: effect of hospital volume on patient outcome. Langenbecks Arch Surg 397(2):201–207

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We would like to thank Dr. Lars Borgman (Center for Higher Education, Dortmund University, Germany) for his statistical support.

Conflicts of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Klaus K. J. Hallfeldt.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sommerey, S., Foroghi, Y., Chiapponi, C. et al. Laparoscopic adrenalectomy—10-year experience at a teaching hospital. Langenbecks Arch Surg 400, 341–347 (2015). https://doi.org/10.1007/s00423-015-1287-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00423-015-1287-x

Keywords

Navigation