Skip to main content

Advertisement

SpringerLink
Log in

Impact of previous cardiovascular surgery on postoperative morbidity and mortality after major pulmonary resection for non-small cell lung cancer

  • Original Article
  • Published:
Langenbeck's Archives of Surgery Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study was to evaluate the impact of previous cardiovascular surgery on the postoperative morbidity and mortality following major pulmonary resection for non-small cell lung cancer (NSCLC).

Methods

Medical records of 227 patients, who underwent major pulmonary resection for NSCLC from 2003 to 2012 at our department, were reviewed retrospectively. Thirty-one patients with a mean age of 65.8 years had previous cardiovascular surgery (group A) including coronary artery revascularization in 11 patients, peripheral arterial revascularization in 6 patients, carotis endarterectomy in 9 patients, and combined coronary artery revascularization and carotis endarterectomy in 5 patients, whereas 167 patients (mean age = 62.0 years) had no cardiovascular comorbidity (group B). Twenty-nine patients with nonsurgically treated cardiovascular comorbidity were excluded from this study.

Results

There were no significant differences in overall postoperative morbidity (22.6 % in group A vs. 19.2 % in group B) and mortality (no mortality in group A vs. 2.4 % in group B) between both groups.

Conclusions

Major pulmonary resections for NSCLC can be performed safely in patients with previous cardiovascular surgical history who are fulfilling the common cardiopulmonary criteria of operability. Operative risk in this subpopulation is comparable to that in patients without cardiovascular comorbidity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Janssen-Heijnen ML, Schipper RM, Razenberg PP, Crommelin MA, Coebergh JW (1998) Prevalence of co-morbidity in lung cancer patients and its relationship with treatment: a population based study. Lung Cancer 21:105–113

    Article  PubMed  CAS  Google Scholar 

  2. Ambrogi V, Pompeo E, Elia S, Pistolese GR, Mineo TC (2003) The impact of cardiovascular comorbidity on the outcome of surgery for stage I and II non-small cell lung cancer. Eur J Cardiothorac Surg 23:811–817

    Article  PubMed  Google Scholar 

  3. Pavia R, Spinelli F, Monaco M, Mondello B, Monaco F, Gaeta R (2007) Lung cancer and cardiovascular diseases: occurrence, comorbidity and surgical timing. J Cardiovasc Surg 48:227–31

    CAS  Google Scholar 

  4. Volpino P, Cangemi R, Fiori E, Cangemi B, De Cesare A, Corsi N, Di Cello T, Cangemi V (2007) Risk of mortality from cardiovascular and respiratory causes in patients with chronic obstructive pulmonary disease submitted to follow-up after lung resection for non-small cell lung cancer. J Cardiovasc Surg 48:375–83

    CAS  Google Scholar 

  5. Janssen-Heijnen ML, Maas HA, Houterman S, Lemmens VE, Rutten HJ, Coebergh JW (2007) Comorbidity in older surgical cancer patients: influence on patient care and outcome. Eur J Cancer 43:2179–93

    Article  PubMed  Google Scholar 

  6. Thomas P, Giudicelli R, Guillen JC, Fuentes P (1994) Is lung cancer surgery justified in patients with coronary artery disease? Eur J Cardiothorac Surg 8:287–91

    Article  PubMed  CAS  Google Scholar 

  7. Ciriaco P, Carretta A, Calori G, Mazzone P, Zannini P (2002) Lung resection for cancer in patients with coronary arterial disease: analysis of short-term results. Eur J Cardiothorac Surg 22:35–40

    Article  PubMed  Google Scholar 

  8. Eagle KA, Rihal CS, Mickel MC, Holmes DR, Foster ED, Gersh BJ (1997) Cardiac risk of noncardiac surgery: influence of coronary disease and type of surgery in 3368 patients. CASS Investigators and University of Michigan Heart Care Program. Coronary Artery Surgery Study. Circulation 16:1882–7

    Article  Google Scholar 

  9. Brunelli A, Charloux A, Bolliger CT, Rocco G, Sculier JP, Varela G, Licker M, Ferguson MK, Faivre-Finn C, Huber RM, Clini EM, Win T, De Ruysscher D, Goldman L (2009) ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J 34:17–41

    Article  PubMed  CAS  Google Scholar 

  10. Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Tarkington LG, Yancy CW (2007) ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions. Soci Vasc Med Biol Soci Vasc Surgery Circulation 116(17):e 418–99

    Google Scholar 

  11. Rami-Porta R, Crowley JJ, Goldstraw P (2009) The revised TNM staging system for lung cancer. Ann Thorac Cardiovasc Surg 15:4–9

    PubMed  Google Scholar 

  12. Travis WD, Colby TV, Corrin B (1999) In collaboration with Sobin LH and pathologists from 14 countries. World Health Organization international histological classification of tumours. Histological typing of lung and pleural tumours, 3rd edn. Springer, Berlin

    Book  Google Scholar 

  13. Reicher-Reiss H, Jonas M, Goldbourt U, Boyko V, Modan B (2001) Selectively increased risk of cancer in men with coronary heart disease. Am J Cardiol 87:459–62

    Article  PubMed  CAS  Google Scholar 

  14. Licker M, de Perrot M, Hohn L, Tschopp JM, Robert J, Frey JG, Schweizer A, Spiliopoulos A (1999) Perioperative mortality and major cardio-pulmonary complications after lung surgery for non-small cell carcinoma. Eur J Cardiothorac Surg 15:314–9

    Article  PubMed  CAS  Google Scholar 

  15. Dominguez-Ventura A, Allen MS, Cassivi SD, Nichols FC 3rd, Deschamps C, Pairolero PC (2006) Lung cancer in octogenarians: factors affecting morbidity and mortality after pulmonary resection. Ann Thorac Surg 82:1175–1179

    Article  PubMed  Google Scholar 

  16. Hosoba S, Hanaoka J, Suzuki T, Takashima N, Kambara A, Matsubayashi K, Asai T (2012) Early to midterm results of cardiac surgery with concomitant pulmonary resection. Ann Thorac Cardiovasc Surg 18:8–11

    Article  PubMed  Google Scholar 

  17. Vojacek J, Hlubocky J, Burkert J, Brazdil J, Durpekt R, Valek S, Spatenka J, Lischke R, Schützner J, Smejkal P, Horacek M, Pafko P, Pavel P (2006) Simultaneous cardiac and thoracic operations. Zentralbl Chir 131:200–205

    Article  PubMed  CAS  Google Scholar 

  18. Saxena P, Tam RK (2004) Combined off-pump coronary artery bypass surgery and pulmonary resection. Ann Thorac Surg 78:498–501

    Article  PubMed  Google Scholar 

  19. Voets AJ, Joesoef KS, van Teeffelen ME (1997) Synchroneously occurring lung cancer (stages I–II) and coronary artery disease: concomitant versus staged surgical approach. Eur J Cardiothorac Surg 12:713–717

    Article  PubMed  CAS  Google Scholar 

  20. Johnson JA, Landreneau RJ, Boley TM, Haggerty SP, Hattler SP, Curtis JJ, Hazelrigg SR (1996) Should pulmonary lesions be resected at the time of open heart surgery? Am Surg 62:300–303

    PubMed  CAS  Google Scholar 

  21. Morishita K, Kawaharada N, Watanabe T, Koshima R, Fujisawa Y, Watanabe A, Kusajima K, Koshino T, Fukada J, Abe T (2001) Simultaneous cardiac operations with pulmonary resection for lung carcinoma. Jpn J Thorac Cardiovasc Surg 49:685–689

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

The authors gratefully acknowledge the support of Dr. Abugameh and Dr. Schnelle, who provided valuable advice during data collection and manuscript preparation.

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Department of Cardiothoracic and Vascular Surgery, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany

    Ömer Senbaklavaci, Hakan Taspinar, Marc Hartert & Christian F. Vahl

Authors
  1. Ömer Senbaklavaci
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hakan Taspinar
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marc Hartert
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Christian F. Vahl
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ömer Senbaklavaci.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Senbaklavaci, Ö., Taspinar, H., Hartert, M. et al. Impact of previous cardiovascular surgery on postoperative morbidity and mortality after major pulmonary resection for non-small cell lung cancer. Langenbecks Arch Surg 398, 903–907 (2013). https://doi.org/10.1007/s00423-013-1081-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00423-013-1081-6

Keywords

Search

Navigation