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Does tumor size have an impact on gastric cancer? A single institute experience

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Abstract

Purpose

The present study investigated the prognostic significance of tumor size in gastric carcinoma patients.

Methods

Nine hundred seventy-three gastric carcinoma patients who underwent curative gastrectomy were included and hospital records were reviewed to determine the relationship between tumor size and survival.

Results

First, the patients were divided based on the mean value of the tumor size in respective stages to control selection bias. Only in stages I and III was tumor size a significant independent prognostic factor. Second, we analyzed the appropriate cutoff value for the large tumor. The minimum criterion for a large tumor, which was determined by the receiver-operating characteristic curve for cancer-related death, was 3.5 cm. There were significant differences between patients with large and small tumors with respect to depth of invasion, number of lymph node metastasis, and stage of disease.

Conclusions

Tumor size serves as an indicator of prognosis in gastric cancer patients and a tumor size of 3.5 cm can be used as a significant lower limit of standard size criterion.

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Authors and Affiliations

  1. Department of Surgery, St. Vincent’s Hospital, The Catholic University of Korea, 93-6 Ji-Dong, Paldal-Gu, Suwon, Kyonggi-Do, 442-723, Korea

    Kyong Hwa Jun, Hyung Min Chin & Woo Bae Park

  2. Department of Surgery, Samsung Medical Center, Seoul, Korea

    Hun Jung

  3. Department of Surgery, Holy Family Hospital, The Catholic University of Korea, Bucheon, Korea

    Jong Min Baek

Authors
  1. Kyong Hwa Jun
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  2. Hun Jung
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  3. Jong Min Baek
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  4. Hyung Min Chin
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  5. Woo Bae Park
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Corresponding author

Correspondence to Hyung Min Chin.

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Jun, K.H., Jung, H., Baek, J.M. et al. Does tumor size have an impact on gastric cancer? A single institute experience. Langenbecks Arch Surg 394, 631–635 (2009). https://doi.org/10.1007/s00423-008-0417-0

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  • DOI: https://doi.org/10.1007/s00423-008-0417-0

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