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Partial splenic embolization: long-term outcome

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Abstract

Background

Partial splenic embolization (PSE) was introduced in the 1980s. We studied the long-term follow-up results of a PSE-treated patient cohort.

Patients and methods

Twenty-six severely ill patients (median age 63.5 years) were treated with a graded PSE a total of 52 times, mainly due to bleeding esophageal varices and thrombocytopenia. The aggregated follow-up time was 1715 months.

Results

The mean values of hemoglobin, leukocytes and thrombocytes increased significantly after PSE. The frequency of bleeding episodes from esophageal varices was significantly reduced. No effect was observed concerning blood liver parameters in cirrhotic patients. The integrated PSE effect was judged as improvement in 19 patients, status quo in 5, and deterioration in 2. Median survival time was 50.5 months (range 0.5–272 months). Two patients underwent liver transplantation. Complications consisted mainly of fever, atelectasis, and abdominal pain. Two patients died of PSE-related complications.

Conclusions

A standardized and graded PSE is reasonably safe even in patients with advanced disease in whom it is hazardous to splenectomize. It gives a long-term effect on the hematological parameters, bleedings from esophageal varices and good palliation, and improved clinical status contributing to symptomatic control.

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Acknowledgements

Valuable medical and linguistic comments from Dr. John Jorgensen, Sydney, are gratefully acknowledged.

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Authors and Affiliations

  1. Department of Surgery, University Hospital of Lund, Lund, Sweden

    Birger Pålsson, Magnus Hallén, Annika Mandahl Forsberg & Anders Alwmark

  2. Department of Surgery, University Hospital of Malmö, Lund University, 20502, Malmö, Sweden

    Birger Pålsson

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  1. Birger Pålsson
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  2. Magnus Hallén
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  3. Annika Mandahl Forsberg
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  4. Anders Alwmark
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Correspondence to Birger Pålsson.

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Pålsson, B., Hallén, M., Forsberg, A.M. et al. Partial splenic embolization: long-term outcome. Langenbecks Arch Surg 387, 421–426 (2003). https://doi.org/10.1007/s00423-002-0342-6

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  • DOI: https://doi.org/10.1007/s00423-002-0342-6

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