Muscle alterations induced by electrostimulation are lower at short quadriceps femoris length

Abstract

Purpose

This study aimed at determining through MRI investigations, force and soreness assessments whether the modulation of muscle length is a relevant strategy for minimising neuromuscular electrical stimulation (NMES)-induced muscle damage in young healthy participants.

Methods

Comparison of 2 NMES sessions (40 isometric electrically-evoked contractions of the knee extensors) was randomly performed on 1 knee flexed at 50° (short muscle length) and the contralateral at 100° (long muscle length) in a single group of healthy participants. Indirect markers of muscle damage including changes in maximal voluntary isometric contraction (MVC) force, muscle volume and transverse relaxation time (T2) were measured before, 2 days (D2), 4 days (D4) and 7 days (D7) after the NMES sessions in each limb of the ten participants.

Results

Although stimulation intensity was similar during the NMES session on both limbs, significantly lower force production was recorded at long muscle length (peak at 30 ± 5% MVC force) as compared to short muscle length (peak at 61 ± 12% MVC force). In the following days, MVC force at long muscle length was decreased from D2 to D7, whereas no significant change occurred at short muscle length. Increases in muscle volume and T2 were found at each time point in stimulated muscles at long muscle length, whereas no change was found at short muscle length.

Conclusion

For the same stimulation intensity, NMES-induced isometric contractions generate higher knee extension force output and result in lower muscle tissues alterations that could be related to a lower intramuscular shear strain when exercise is performed at short muscle length.

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Abbreviations

ANOVA:

Analysis of variance

D2:

Day #2

D4:

Day #4

D7:

Day #7

MRI:

Magnetic resonance imaging

MVC:

Maximal voluntary contraction

NMES:

Neuromuscular electrical stimulation

POST:

Immediately after the NMES session

PRE:

Before the NMES session

RF:

rectus femoris

SAR:

sartorius

T 2 :

Transverse relaxation time

VAS:

Visual analog scale

VI:

vastus intermedius

VL:

vastus lateralis

VM:

vastus medialis

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Acknowledgements

This study was supported by the Centre National de la Recherche Scientifique (CNRS UMR 7339) and the Assistance Publique des Hôpitaux de Marseille (APHM). The authors thank all the subjects who participated in the present study.

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AF and JG conceived and designed research. AF conducted experiments. AF and ACO analysed the data. AF, JG, DB wrote the manuscript. All authors read and approved the manuscript.

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Correspondence to Alexandre Fouré or Julien Gondin.

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Fouré, A., Ogier, A.C., Guye, M. et al. Muscle alterations induced by electrostimulation are lower at short quadriceps femoris length. Eur J Appl Physiol 120, 325–335 (2020). https://doi.org/10.1007/s00421-019-04277-5

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Keywords

  • MRI
  • Muscle damage
  • Acute exercise
  • Neuromuscular electrical stimulation
  • Muscle strength
  • Thigh