Abstract
Purpose
High-intensity training is recognised as a time-efficient way of improving aerobic fitness. However, there is a lack of consensus regarding the temporal nature of adaptation response and which peripheral and cardiac changes occur using the same exercise stimulus and protocol. Therefore, this study aimed to evaluate the progression of vascular and cardiac changes over a 6-week training period.
Methods
Twelve healthy males (age 21 ± 2 years; 42.5 ± 8.3 ml min−1 kg−1) participated in a high-intensity training programme consisting of 1-min sprints, interspersed with 2 min active recovery, 3 days/week for 6 weeks on a cycle ergometer. Cardiac, vascular, blood lipids and VO2max measurements were taken at 0, 3 and 6 weeks and compared against a participant-matched control group (age 21 ± 2 years; 37.7 ± 8.3 ml min−1 kg−1).
Results
There was a significant improvement in VO2max (42.5 ± 8.3–47.4 ± 8.5 ml min−1 kg−1; p = 0.009) in the training group and a significant decrease in systolic blood pressure (8%) from 0 to 6 weeks (p = 0.025). There was a small yet significant decrease in ejection fraction and increased end-systolic volume in both groups over time (p = 0.01) with no significant interaction effect (p > 0.05). A between-group difference in peak velocity of early diastolic mitral annular motion was also observed (p = 0.01). No improvements were seen in blood lipid profiles, central arterial stiffness and cardiometabolic risk score.
Conclusions
Six weeks of high-intensity training increases aerobic fitness and is enough to stimulate initial reductions in peripheral pressure, but not sufficient to elicit structural and functional cardiac changes, reduce arterial stiffness or lower CV risk.
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Abbreviations
- A:
-
Peak velocity of late transmitral flow
- A’:
-
Peak velocity of diastolic mitral annular motion
- Alx:
-
Augmentation index
- AP:
-
Central augmented pressure
- a-VDO2 :
-
Arterial–venous difference
- BMI:
-
Body mass index
- COmax :
-
Maximal cardiac output
- CRF:
-
Cardiorespiratory fitness
- CVD:
-
Cardiovascular disease
- DBP:
-
Diastolic blood pressure
- DP:
-
Central aortic diastolic pressure
- E:
-
Peak velocity of early diastolic transmitral flow
- E’:
-
Peak velocity of early diastolic mitral annular motion
- EF:
-
Ejection fraction
- FBG:
-
Fasting blood glucose
- HDL-C:
-
High-density lipoprotein cholesterol
- HIIT:
-
High-intensity interval training
- HR:
-
Heart rate
- IVSd:
-
Interventricular septum thickness at end diastole
- LDL-C:
-
Low-density lipoprotein cholesterol
- LV:
-
Left ventricle
- LVEDV:
-
Left ventricular end-diastolic volume
- LVESV:
-
Left ventricular end-systolic volume
- LVIDd:
-
Left ventricular internal diameter end diastole
- LVIDs:
-
Left ventricular internal diameter end systole
- LVPWd:
-
Left ventricular posterior wall thickness at end diastole
- MAP:
-
Mean arterial pressure
- NO:
-
Nitric oxide
- PP:
-
Central aortic pulse pressure
- PWV:
-
Pulse wave velocity
- S’:
-
Peak velocity of systolic mitral annular motion
- SBP:
-
Systolic blood pressure
- SIT:
-
Sprint interval training
- SP:
-
Central aortic systolic pressure
- SV:
-
Stroke volume
- SVmax :
-
Maximal stroke volume
- TC:
-
Total cholesterol
- TG:
-
Triglycerides
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Acknowledgements
We would like to thank Mark Bell and Sean Muirhead for their contribution to the exercise programme.
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KH, DR and PA conceived and designed research. KH, DR and PA conducted experiments. KH, PA were involved in data analysis. KH and PA wrote the manuscript, with DR acting as advisor.
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Communicated by Anni Vanhatalo.
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Holloway, K., Roche, D. & Angell, P. Evaluating the progressive cardiovascular health benefits of short-term high-intensity interval training. Eur J Appl Physiol 118, 2259–2268 (2018). https://doi.org/10.1007/s00421-018-3952-6
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DOI: https://doi.org/10.1007/s00421-018-3952-6