Low-volume high-intensity swim training is superior to high-volume low-intensity training in relation to insulin sensitivity and glucose control in inactive middle-aged women
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We tested the hypothesis that low-volume high-intensity swimming has a larger impact on insulin sensitivity and glucose control than high-volume low-intensity swimming in inactive premenopausal women with mild hypertension.
Sixty-two untrained premenopausal women were randomised to an inactive control (n = 20; CON), a high-intensity low-volume (n = 21; HIT) or a low-intensity high-volume (n = 21; LIT) training group. During the 15-week intervention period, HIT performed 3 weekly 6–10 × 30-s all-out swimming intervals (average heart rate (HR) = 86 ± 3 % HRmax) interspersed by 2-min recovery periods and LIT swam continuously for 1 h at low intensity (average HR = 73 ± 3 % HRmax). Fasting blood samples were taken and an oral glucose tolerance test (OGTT) was conducted pre- and post-intervention.
After HIT, resting plasma [insulin] was lowered (17 ± 34 %; P < 0.05) but remained similar after LIT and CON. Following HIT, 60-min OGTT plasma [insulin] and [glucose] was lowered (24 ± 30 % and 10 ± 16 %; P < 0.05) but remained similar after LIT and CON. Total area under the curve for plasma [glucose] was lower (P < 0.05) after HIT than LIT (660 ± 141 vs. 860 ± 325 mmol min L−1). Insulin sensitivity (HOMA-IR) had increased (P < 0.05) by 22 ± 34 % after HIT, with no significant change after LIT or CON, respectively. Plasma soluble intracellular cell adhesion molecule 1 was lowered (P < 0.05) by 4 ± 8 and 3 ± 9 % after HIT and CON, respectively, while plasma soluble vascular cell adhesion molecule 1 had decreased (P < 0.05) by 8 ± 23 % after HIT only.
These findings suggest that low-volume high-intensity intermittent swimming is an effective and time-efficient training strategy for improving insulin sensitivity, glucose control and biomarkers of vascular function in inactive, middle-aged mildly hypertensive women.
KeywordsBlood glucose Type 2 diabetes Body composition Upper body exercise Metabolic health
Analysis of variance
Homeostatic model assessment of insulin resistance
Oral glucose tolerance test
Standard error of the mean
Soluble intracellular cell adhesion molecule 1
Soluble vascular cell adhesion molecule 1
Type 2 diabetes mellitus
Total area under the curve
The authors would like to express their appreciation for the outstanding efforts and positive attitude of the participants. In addition, they are extremely grateful for the professional assistance given by swimming coaches Remi Lamhauge, Brynhild Klein, Pauli Øssursson Mohr, Heini Rasmussen, Oluffa á Høvdanum, and the late Jákup Mohr, and for the technical support provided by Ivy Hansen, Gunnrið Jóannesarson, Guðrið Andórsdóttir, Hergerð Joensen, Ann Østerø, Ebba Andreassen, Maud av Fløtum, Liljan av Fløtum Petersen, Marjun Thomsen, Annika Lindenskov, Jann Mortensen, David Childs, Sarah R. Jackman and Jens Jung Nielsen. The study was supported by a Grant from the Faroese Research Council, as well as by The Faroese Confederation of Sports and Olympic Committee (Ítróttarsamband Føroya), and the Danish Sports Confederation (Danmarks Idrætsforbund). In addition, financial support was obtained from Eik Bank.
Compliance with ethical standards
Conflict of interest
The authors declare that there is no conflict of interests
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
- Arad AD, DiMenna FJ, Thomas N, Tamis-Holland J, Weil R, Geliebter A, Albu JB (2015) High-intensity interval training without weight loss improves exercise but not basal or insulin-induced metabolism in overweight/obese African American women. J Appl Physiol 119:352–362. doi: 10.1152/japplphysiol.00306.2015 CrossRefPubMedGoogle Scholar
- Burgomaster KA, Cermak NM, Phillips SM, Benton CR, Bonen A, Gibala MJ (2007) Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detraining. Am J Physiol Regul Integr Comp Physiol 292:R1970–R1976. doi: 10.1152/ajpregu.00503.2006 CrossRefPubMedGoogle Scholar
- Chen NG, Azhar S, Abbasi F, Carantoni M, Reaven GM (2000) The relationship between plasma glucose and insulin responses to oral glucose, LDL oxidation, and soluble intercellular adhesion molecule-1 in healthy volunteers. Atherosclerosis 152:203–208. doi: 10.1016/S0021-9150(99)00460-8 CrossRefPubMedGoogle Scholar
- Ciolac EG, Bocchi EA, Bortolotto LA, Carvalho VO, Greve JM, Guimaraes GV (2010) Effects of high-intensity aerobic interval training vs. moderate exercise on hemodynamic, metabolic and neuro-humoral abnormalities of young normotensive women at high familial risk for hypertension. Hypertens Res 33:836–843. doi: 10.1038/hr.2010.72 CrossRefPubMedGoogle Scholar
- Cox KL, Burke V, Beilin LJ, Puddey IB (2010) A comparison of the effects of swimming and walking on body weight, fat distribution, lipids, glucose, and insulin in older women-the Sedentary Women Exercise Adherence Trial 2. Metabolism 59:1562–1573. doi: 10.1016/j.metabol.2010.02.001 CrossRefPubMedGoogle Scholar
- Glowinska B, Urban M, Peczynska J, Florys B (2005) Soluble adhesion molecules (sICAM-1, sVCAM-1) and selectins (sE selectin, sP selectin, sL selectin) levels in children and adolescents with obesity, hypertension, and diabetes. Metabolism 54:1020–1026. doi: 10.1016/j.metabol.2005.03.004 CrossRefPubMedGoogle Scholar
- Iaia FM, Hellsten Y, Nielsen JJ, Fernstrom M, Sahlin K, Bangsbo J (2009) Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volume. J Appl Physiol 106:73–80. doi: 10.1152/japplphysiol.90676.2008 CrossRefPubMedGoogle Scholar
- Mohr M, Krustrup P, Nielsen JJ, Nybo L, Rasmussen MK, Juel C, Bangsbo J (2007) Effect of two different intense training regimens on skeletal muscle ion transport proteins and fatigue development. Am J Physiol Regul Integr Comp Physiol 292:R1594–R1602. doi: 10.1152/ajpregu.00251.2006 CrossRefPubMedGoogle Scholar
- Motta VF, Aguila MB, Mandarim-De-Lacerda CA (2015) High-intensity interval training (swimming) significantly improves the adverse metabolism and comorbidities in diet-induced obese mice. The Journal of Sports Medicine and Physical Fitness 54:203–209Google Scholar
- Nyberg M, Seidelin K, Andersen TR, Overby NN, Hellsten Y, Bangsbo J (2014) Biomarkers of vascular function in premenopausal and recent postmenopausal women of similar age: effect of exercise training. Am J Physiol Regul Integr Comp Physiol 306:R510–R517. doi: 10.1152/ajpregu.00539.2013 CrossRefPubMedGoogle Scholar
- Rizzoli R et al (2014) The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas 79:122–132. doi: 10.1016/j.maturitas.2014.07.005 CrossRefPubMedGoogle Scholar
- World Health Organization (2016) Physical Inactivity: A Global Public Health Problem. http://www.who.int/dietphysicalactivity/factsheet_inactivity/en/. Accessed 11/03/16 2016