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A beat-by-beat analysis of cardiovascular responses to dry resting and exercise apnoeas in elite divers

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European Journal of Applied Physiology Aims and scope Submit manuscript

Abstract

Purpose

Cardiovascular responses during resting apnoea include three phases: (1) a dynamic phase of rapid changes, lasting at most 30 s; (2) a subsequent steady phase; and (3) a further dynamic phase, with a continuous decrease in heart rate (HR) and an increase in blood pressure. The interpretation was that the end of the steady phase corresponds to the physiological apnoea breaking point. This being so, during exercise apnoeas, the steady phase would be shorter, and the rate of cardiovascular changes in the subsequent unsteady phase would be faster than at rest.

Methods

To test these hypotheses, we measured beat-by-beat systolic (SBP), diastolic, and mean blood pressures (MBP), HR, and stroke volume (SV) in six divers during dry resting (duration 239.4 ± 51.6 s) and exercise (30 W on cycle ergometer, duration 88.2 ± 20.9 s) maximal apnoeas, and we computed cardiac output (\(\dot{Q}\)) and total peripheral resistance (TPR).

Results

Compared to control, at the beginning of resting (R1) and exercising (E1) apnoeas, SBP and MBP decreased and HR increased. SV and \(\dot{Q}\) fell, so that TPR remained unchanged. At rest, HR, SV, \(\dot{Q}\), and SBP were stable during the subsequent phase; this steady phase was missing in exercise apnoeas. Subsequently, at rest (R3) and at exercise (E2), HR decreased and SBP increased continuously. SV returned to control values. Since \(\dot{Q}\) remained unchanged, TPR grew.

Conclusions

The lack of steady phase during exercise apnoeas suggests that the conditions determining R3 were already attained at the end of E1. This being so, E2 would correspond to R3.

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Abbreviations

DBP:

Diastolic blood pressure

E1:

Rapid transition phase of apnoea at exercise

E2:

Readjustment phase of apnoea at exercise

HR:

Heart rate

MBP:

Mean blood pressure

\(\dot{Q}\) :

Cardiac output

R1:

Rapid transition phase of apnoea at rest

R2:

Steady state phase of apnoea at rest

R3:

Readjustment phase of apnoea at rest

SaO2 :

Arterial oxygen saturation

SBP:

Systolic blood pressure

SD:

Standard deviation

SV:

Stroke volume

TPR:

Total peripheral resistance

\(\dot{V}E\) :

Expired ventilation

\(\dot{V}{\rm O}_{2}\) :

Oxygen uptake

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Acknowledgments

The study was supported by a Grant from the University of Brescia to Guido Ferretti and by Swiss National Science Foundation Grant 32003B_144259 to Guido Ferretti. We are grateful to Dr. Nicola Sponsiello for collaboration in subjects’ recruitment.

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Correspondence to Guido Ferretti.

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Communicated by David C. Poole.

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Sivieri, A., Fagoni, N., Bringard, A. et al. A beat-by-beat analysis of cardiovascular responses to dry resting and exercise apnoeas in elite divers. Eur J Appl Physiol 115, 119–128 (2015). https://doi.org/10.1007/s00421-014-2992-9

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  • DOI: https://doi.org/10.1007/s00421-014-2992-9

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