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Body regional influences of l-menthol application on the alleviation of heat strain while wearing firefighter’s protective clothing

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Abstract

The purpose of this study was to investigate the influences of menthol application according to the amount of surface area on physiological and psychological heat strains, along with body regional influences. Male students underwent two stages of experiments: [Experiment 1] Cutaneous thermal threshold test at rest on eight body regions with/without a 0.8% menthol application at T a 28°C and 50% RH; [Experiment 2] Six exercise tests with/without a 0.8% menthol spray at T a 28°C and 40% RH, while wearing firefighter’s protective clothing (No menthol, PCNO; Face and neck menthol, PCFN; Upper body menthol, PCUP; Whole body menthol application, PCWB) or wearing normal clothing (No menthol, NCNO; Upper body menthol, NCUP). Experiment 1 showed that menthol caused no significant influence on cutaneous warm thresholds, while menthol applications evoked earlier detection of cool sensations, especially on the chest (P = 0.043). Experiment 2 revealed that NCUP, PCUP and PCWB caused lower mean skin temperature, especially with higher peripheral vasoconstrictions on the extremities at rest. During exercise, NCUP, PCUP and PCWB induced greater and earlier increases in rectal temperatures (T re) and a delayed sweat response, but lessened psychological burdens (P < 0.05). Both physiological and psychological effects of PCFN were insignificant. For a composite analysis, individual Menthol Sensitivity Index at cooling in Experiment 1 had significant relationships with the threshold for T re increase and changes in heart rate in NCUP of Experiment 2 (P < 0.05). Our results indicate that menthol’s topical influence is body region-dependent, as well as depending on the exposed body surface area.

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References

  • Bakri I, Lee JY, Nakao K, Wakabayashi H, Tochihara Y (2011) Effects of different harness design of self-contained breathing apparatus for firefighting on physiological responses in neutral and hot environments. 14th International Congress on Environmental Ergonomics (14th ICEE), Greece, pp 281−284

  • Barr D, Gregson W, Reilly T (2010) The thermal ergonomics of firefighting reviewed. Appl Ergon 41:161–172

    Article  PubMed  Google Scholar 

  • Bazett HC (1949) The regulation of body temperature. In: Newburgh LH (ed) Physiology of heat regulation and the science of clothing. Saunders, Philadelphia, pp 109–192

    Google Scholar 

  • Bligh J (1973) Temperature regulation in mammals and other vertebrates. North Holland Publishing Company, Amsterdam

    Google Scholar 

  • Bligh J (1998) Mammalian homeothermy: an integrative thesis. J Therm Biol 23:143–258

    Article  Google Scholar 

  • Borg GAV (1982) Psychophysical bases of perceived exertion. Med Sci Sports Exe 14:377–381

    CAS  Google Scholar 

  • Cheung SS, Petersen SR, McLellan TM (2010) Physiological strain and countermeasures with firefighting. Scand J Med Sci Sports 20(Suppl. 3):103–116

    Article  PubMed  Google Scholar 

  • Chou C, Tochihara Y, Kim T (2008) Physiological and subjective responses to cooling devices on firefighting protective clothing. Eur J Appl Physiol 104:369–374

    Article  PubMed  Google Scholar 

  • Cliff MA, Green BG (1994) Sensory irritation and coolness produced by menthol: evidence for selective desensitization of irritation. Physiol Behavior 56:1021–1029

    Article  CAS  Google Scholar 

  • Cliff MA, Green BG (1996) Sensitization and desensitization to capsaicin and menthol in the oral cavity: interactions and individual differences. Physiol Behavior 59:487–494

    Article  CAS  Google Scholar 

  • Giesbrecht GG, Jamieson C, Cahill F (2007) Cooling hyperthermic firefighters by immersing forearms and hands in 10°C and 20°C water. Aviat Space Environ Med 78:561–567

    PubMed  Google Scholar 

  • Gillis DJ, House JR, Tipton MJ (2010) The influence of menthol on thermoregulation and perception during exercise in warm, humid conditions. Eur J Applied Physiol 110:609–618

    Article  CAS  Google Scholar 

  • Green BG (1985) Menthol modulates oral sensations of warmth and cold. Physiol Behavior 35:427–434

    Article  CAS  Google Scholar 

  • Green BG (1986) Menthol inhibits the perception of warmth. Physiol Behavior 38:833–838

    Article  CAS  Google Scholar 

  • Green BG (1992) The sensory effect of l-menthol on human skin. Somatosens Mot Res 9(3):235–244

    Article  PubMed  CAS  Google Scholar 

  • Hensel H, Zotterman Y (1951) The effect of menthol on the thermoreceptors. Acta Physiol Scand 24:27–34

    Article  PubMed  CAS  Google Scholar 

  • House JR, Tipton MJ (2002) Using skin temperature gradients or skin heat flux measurements to determine thresholds of vasoconstriction and vasodilation. Eur J Appl Physiol 88:141–145

    Article  PubMed  Google Scholar 

  • Johnson CD, Melanaphy D, Purse A, Stokesberry SA, Dickson P, Zholos AV (2009) Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone. Am J Physiol 296:H1868–H1877

    CAS  Google Scholar 

  • Kim JH, Coca A, Williams WJ, Roberge RJ (2011) Subjective perceptions and ergonomics evaluation of a liquid cooled garment worn under protective ensemble during an intermittent treadmill exercise. Ergonomics 54(7):626–635

    Article  PubMed  Google Scholar 

  • Knowlton WM, McKemy DD (2011) TRPM8: from cold to cancer, peppermint to pain. Curr Pharm Biotechnol 12:68–77

    Article  PubMed  CAS  Google Scholar 

  • Kounalakis SN, Botonis PG, Koskolou MD, Geladas ND (2010) The effect of menthol application to the skin on sweating rate response during exercise in swimmers and controls. Eur J Appl Physiol 109:183–189

    Article  PubMed  CAS  Google Scholar 

  • Kozyerva TV, Tkachenko EY (2008) Effect of menthol on human temperature sensitivity. Human Physiol 34:221–225

    Article  Google Scholar 

  • LeBlanc J, Cote J, Dulac S, Dulong-Turcot F (1978) Effects of age, sex, and physical fitness on responses to local cooling. J Appl Physiol 44:813–817

    PubMed  CAS  Google Scholar 

  • Lee JKW, Shirreffs SM, Maughan RJ (2008a) Cold drink ingestion improves exercise endurance capacity in the heat. Med Sci Sports Exerc 40:1637–1644

    Article  PubMed  Google Scholar 

  • Lee JY, Choi JW, Kim H (2008b) Determination of body surface area and formulas to estimate body surface area using the Alginate method. J Physiol Anthropol 27(2):71–82

    Article  PubMed  Google Scholar 

  • Lee JY, Saat M, Chou C, Hashiguchi N, Wijayanto T, Wakabayashi H, Tochihara Y (2010) Cutaneous warm and cool sensation thresholds and the inter-threshold zone in Malaysian and Japanese males. J Therm Biol 35:70–76

    Article  Google Scholar 

  • McKemy DD, Neuhausser WM, Jullus D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52–58

    Article  PubMed  CAS  Google Scholar 

  • McLellan TM, Selkirk GA (2004) Heat stress while wearing long pants or shorts under firefighting protective clothing. Ergonomics 47:75–90

    Article  PubMed  CAS  Google Scholar 

  • Moran DS, Shitzer A, Pandolf KB (1998) A physiological strain index to evaluate heat stress. Am J Physiol 275(1 Pt 2):R129–R134

    PubMed  CAS  Google Scholar 

  • Mündel T, Jones DA (2010) The effect of swilling an l(−)-menthol solution during exercise in the heat. Eur J Appl Physiol 109:59–65

    Article  PubMed  Google Scholar 

  • Nakayama A (1981) Thermal physiology. Rikougakusha Press, Tokyo

    Google Scholar 

  • Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A (2002) A TRP channel that senses cold stimuli and menthol. Cell 108:705–715

    Article  PubMed  CAS  Google Scholar 

  • Schlader ZJ, Simmons SE, Stannard SR, Mündel T (2011) The independent roles of temperature and thermal perception in the control of human thermoregulatory behavior. Physiol Behav 103:217–224

    Article  PubMed  CAS  Google Scholar 

  • Selkirk GA, McLellan TM, Wong J (2004) Active versus passive cooling during work in warm environments while wearing firefighting protective clothing. J Occup Environ Hyg 1:521–531

    Article  PubMed  CAS  Google Scholar 

  • Tajino K, Matsumura K, Kosada K, Shibakusa T, Inoue K, Fushiki T, Hosokawa H, Kobayashi S (2007) Application of menthol to the skin of whole trunk in mice induces autonomic and behavioral heat-gain responses. Am J Physiol 293:R2128–R2135

    CAS  Google Scholar 

  • Wasner G, Schattschneider J, Binder A, Baron R (2004) Topical menthol—a human model for cold pain by activation and sensitization of C nociceptors. Brain 127:1159–1171

    Article  PubMed  Google Scholar 

  • Werner J, Mekjavic IB, Taylor NAS (2008) Concepts in physiological regulation: a thermoregulatory perspective. In: Taylor NAS, Groeller H (eds) Physiological bases of human performance during work and exercise. Churchhill Livingstone, Elsevier

    Google Scholar 

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Acknowledgments

We would like to express our thanks to Su-Young Son, Mutsuhiro Fujiwara, Shizuka Umezaki, and Eric A. Stone for their technical advice and secretarial support. We are grateful to all subjects for their participation. This study was supported by the Promotion Program for Fire and Disaster Prevention Technologies, Japan.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Environmental Ergonomics Laboratory, Department of Human Science, Faculty of Design, Kyushu University, 4-9-1, Shiobaru, Fukuoka, 815-8540, Minami-ku, Japan

    Joo-Young Lee, Kouhei Nakao, Ilham Bakri & Yutaka Tochihara

  2. Industrial Engineering Department, Hasanuddin University, Makassar, Indonesia

    Ilham Bakri

Authors
  1. Joo-Young Lee
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  2. Kouhei Nakao
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  3. Ilham Bakri
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  4. Yutaka Tochihara
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Correspondence to Joo-Young Lee.

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Communicated by George Havenith.

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Lee, JY., Nakao, K., Bakri, I. et al. Body regional influences of l-menthol application on the alleviation of heat strain while wearing firefighter’s protective clothing. Eur J Appl Physiol 112, 2171–2183 (2012). https://doi.org/10.1007/s00421-011-2192-9

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  • DOI: https://doi.org/10.1007/s00421-011-2192-9

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