Abstract
Quantitative data on muscle volume (MV) are important for estimating maximal muscle power. The objective of this study was to determine the correlation between anatomical cross-sectional areas (ACSAs) and the MV in thigh muscles (extensors, flexors, adductors, and sartorius) in perimenopausal women, and to identify at which proximal-to-distal level a single-slice ACSA measurement with magnetic resonance imaging (MRI) displays the highest correlation in each of these. Axial MRIs of the thigh were acquired in 41 perimenopausal women aged 50.8 ± 3.2 years. Segmentation of the extensors, flexors, adductors, and the sartorius was performed between the femoral neck (0%) and the distal end of the intermediate vastus (100%). MVs were determined by numerical integration, and the ACSA was calculated from three-dimensional reconstructions at 10% intervals from proximal to distal. The extensors contributed 50%, the flexors 19%, the adductors 28%, and the sartorius 3% of the total thigh MV. Maximal correlations between ACSA and MV were observed at the 20–40% proximal-to-distal level in the extensors (R 2 = 0.73), at 30% in the adductors (R 2 = 0.82), and at 70% in the flexors (R 2 = 0.72) and sartorius (R 2 = 0.85), respectively. ACSA at 50% displayed the highest overall correlations (R 2 ≥ 0.69) with MV for all muscle groups. Single-slice ACSAs from MRI displayed high correlations with MVs. Although the (proximal to distal) measurement locations with the highest correlation varied between the muscle groups, a single slice at the 50% location achieved the best compromise in terms of correlation between ACSA and MV across extensors, flexors, adductors and the sartorius.
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References
Abe T, Brechue WF, Fujita S, Brown JB (1998) Gender differences in FFM accumulation and architectural characteristics of muscle. Med Sci Sports Exerc 30:1066–1070
Abe T, Kumagai K, Brechue WF (2000) Fascicle length of leg muscles is greater in sprinters than distance runners. Med Sci Sports Exerc 32:1125–1129
Akagi R, Takai Y, Ohta M, Kanehisa H, Kawakami Y, Fukunaga T (2009) Muscle volume compared to cross-sectional area is more appropriate for evaluating muscle strength in young and elderly individuals. Age Ageing 38(5):564–569
Berg HE, Tedner B, Tesch PA (1993) Changes in lower limb muscle cross-sectional area and tissue fluid volume after transition from standing to supine. Acta Physiol Scand 148:379–385
Blazevich AJ, Coleman DR, Horne S, Cannavan D (2009) Anatomical predictors of maximum isometric and concentric knee extensor moment. Eur J Appl Physiol 105:869–878
De Ste CM, Deighan M, Armstrong N (2003) Assessment and interpretation of isokinetic muscle strength during growth and maturation. Sports Med 33:727–743
Doherty TJ (2003) Invited review: aging and sarcopenia. J Appl Physiol 95:1717–1727
Fukunaga T, Roy RR, Shellock FG, Hodgson JA, Edgerton VR (1996) Specific tension of human plantar flexors and dorsiflexors. J Appl Physiol 80:158–165
Fukunaga T, Miyatani M, Tachi M, Kouzaki M, Kawakami Y, Kanehisa H (2001) Muscle volume is a major determinant of joint torque in humans. Acta Physiol Scand 172:249–255
Kanehisa H, Ikegawa S, Tsunoda N, Fukunaga T (1994) Strength and cross-sectional area of knee extensor muscles in children. Eur J Appl Physiol Occup Physiol 68:402–405
Kawakami Y, Abe T, Fukunaga T (1993) Muscle-fiber pennation angles are greater in hypertrophied than in normal muscles. J Appl Physiol 74:2740–2744
Kawakami Y, Abe T, Kuno SY, Fukunaga T (1995) Training-induced changes in muscle architecture and specific tension. Eur J Appl Physiol Occup Physiol 72:37–43
Kubo K, Kanehisa H, Azuma K, Ishizu M, Kuno SY, Okada M, Fukunaga T (2003) Muscle architectural characteristics in young and elderly men and women. Int J Sports Med 24:125–130
Macaluso A, De Vito G (2004) Muscle strength, power and adaptations to resistance training in older people. Eur J Appl Physiol 91:450–472
Maganaris CN, Baltzopoulos V, Tsaopoulos D (2006) Muscle fibre length-to-moment arm ratios in the human lower limb determined in vivo. J Biomech 39:1663–1668
Morse CI, Degens H, Jones DA (2007) The validity of estimating quadriceps volume from single MRI cross-sections in young men. Eur J Appl Physiol 100:267–274
Narici MV, Roi GS, Landoni L, Minetti AE, Cerretelli P (1989) Changes in force, cross-sectional area and neural activation during strength training and detraining of the human quadriceps. Eur J Appl Physiol Occup Physiol 59:310–319
Narici MV, Landoni L, Minetti AE (1992) Assessment of human knee extensor muscles stress from in vivo physiological cross-sectional area and strength measurements. Eur J Appl Physiol Occup Physiol 65:438–444
Narici MV, Maffulli N, Maganaris CN (2008) Ageing of human muscles and tendons. Disabil Rehabil 30:1548–1554
Raj IS, Bird SR, Shield AJ (2010) Aging and the force-velocity relationship of muscles. Exp Gerontol 45:81–90
Ring-Dimitriou S, Steinbacher P, von Duvillard SP, Kaessmann H, Muller E, Sanger AM (2009) Exercise modality and physical fitness in perimenopausal women. Eur J Appl Physiol 105:739–747
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We would like to thank the Paracelsus Medical University Forschungsfond for supporting this study and the participants who volunteered to take part in this MRI study.
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Communicated by Arnold de Haan.
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Cotofana, S., Hudelmaier, M., Wirth, W. et al. Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women. Eur J Appl Physiol 110, 91–97 (2010). https://doi.org/10.1007/s00421-010-1477-8
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DOI: https://doi.org/10.1007/s00421-010-1477-8