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Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging

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Abstract

In this study, we assessed the physiological changes after exercising or cooling skeletal muscles on the basis of the apparent diffusion coefficient (ADC) values in magnetic resonance (MR) diffusion-weighted images (DWIs). DWIs of the ankle dorsiflexors were acquired with a 1.5-T MR device before and after exercising (22 subjects) or cooling (19 subjects). The exercise comprised a 5-min walk with the ankles dorsiflexed and a 30-time ankle dorsiflexion. Cooling (0°C) of the ankle dorsiflexors was performed for 30 min. ADC values were calculated as ADC1—reflecting diffusion and perfusion and ADC2—approximating the true diffusion coefficient of the ankle dorsiflexors before and after exercising or cooling. ADC1 and ADC2 significantly increased with exercise and decreased with cooling (P < 0.05). Considering both diffusion and perfusion, ADC values allowed us to evaluate the intramuscular changes induced by exercising or cooling in terms of the motion of water molecules and microcirculation.

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Acknowledgments

This study was funded by a Grant-in-Aid for Scientific Research (Grant-in-Aid for Young Scientists) from the Japanese Ministry of Education, Culture, Sports, Science and Technology.

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Authors and Affiliations

  1. Faculty of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, Saitama, 359-1192, Japan

    Osamu Yanagisawa

  2. Department of Radiological Sciences, School of Health Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2 Ami, Inashiki, Ibaraki, 300-0394, Japan

    Daisuke Shimao

  3. MR Group, Marketing Division, Siemens-Asahi Medical Technologies Ltd, Takanawa Park Tower, 3-20-14 Higashi-Gotanda, Shinagawa-ku, Tokyo, 141-8644, Japan

    Katsuya Maruyama & Matthew Nielsen

Authors
  1. Osamu Yanagisawa
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  2. Daisuke Shimao
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  3. Katsuya Maruyama
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  4. Matthew Nielsen
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Correspondence to Osamu Yanagisawa.

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Yanagisawa, O., Shimao, D., Maruyama, K. et al. Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging. Eur J Appl Physiol 105, 723–729 (2009). https://doi.org/10.1007/s00421-008-0954-9

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  • DOI: https://doi.org/10.1007/s00421-008-0954-9

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