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The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure

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Abstract

Continuous assessment of mixed venous oxygen saturation (cSvO2) during exercise using a fiber optic pulmonary artery catheter can provide valuable information on the physiological determinants of the exercise capacity in patients with chronic heart failure (CHF). Since its accuracy is not well established during exercise, this study evaluated the reliability of a fiber optic pulmonary artery catheter for measuring SvO2 during exercise in CHF patients. Ten patients with stable CHF performed steady-state exercise tests at 30 and 80% of the ventilatory threshold and consequently a symptom-limited incremental exercise test. During the tests, SvO2 was monitored continuously using a fiber optic pulmonary artery catheter (CCOmbo, Edwards Lifesciences, Irvine, CA, USA) and by oximetric analysis of mixed venous blood samples obtained at rest (n = 26), steady state (n = 17) and peak exercise (n = 8). There was a significant correlation between oximetrically determined SvO2 and cSvO2 values (r = 0.97). The bias between both methods was 0.6% with limits of agreement from −8 to 9%. The limits of agreement for SvO2 values <30% (n = 16) were slightly wider than for SvO2 values >30% (n = 35) (from −10 to 12% and from −7 to 8%, respectively). In conclusion, continuous measurement of SvO2 during exercise using a fiber optic pulmonary catheter is reliable in patients with CHF, with somewhat less accurate measurements of SvO2 below 30%.

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References

  • Ahmadizad S, El Sayed MS (2005) The acute effects of resistance exercise on the main determinants of blood rheology. J Sports Sci 23:243–249

    Article  PubMed  Google Scholar 

  • Baele PL, McMichan JC, Marsh HM, Sill JC, Southorn PA (1982) Continuous monitoring of mixed venous oxygen saturation in critically ill patients. Anesth Analg 61:513–517

    Article  PubMed  CAS  Google Scholar 

  • Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60:2020–2027

    PubMed  CAS  Google Scholar 

  • Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310

    PubMed  CAS  Google Scholar 

  • Burchell SA, Yu M, Takiguchi SA, Ohta RM, Myers SA (1997) Evaluation of a continuous cardiac output and mixed venous oxygen saturation catheter in critically ill surgical patients. Crit Care Med 25:388–391

    Article  PubMed  CAS  Google Scholar 

  • Fahey PJ, Harris K, Vanderwarf C (1984) Clinical experience with continuous monitoring of mixed venous oxygen saturation in respiratory failure. Chest 86:748–752

    Article  PubMed  CAS  Google Scholar 

  • Fletcher EC, Miller T, Thornby JI (1988) Accuracy of fiberoptic central venous saturation catheter below 50%. J Appl Physiol 64:2220–2223

    PubMed  CAS  Google Scholar 

  • Matsumoto A, Itoh H, Yokoyama I, Aoyagi T, Sugiura S, Hirata Y, Kato M, Momomura S (1999) Kinetics of oxygen uptake at onset of exercise related to cardiac output, but not to arteriovenous oxygen difference in patients with chronic heart failure. Am J Cardiol 83:1573–1576, A8

    Article  PubMed  CAS  Google Scholar 

  • Nakanishi N, Yoshioka T, Okano Y, Nishimura T (1993) Continuous Fick cardiac output measurement during exercise by monitoring of mixed venous oxygen saturation and oxygen uptake. Chest 104:419–426

    Article  PubMed  CAS  Google Scholar 

  • Stengele E (1995) Measuring continuous Fick cardiac output. Chest 107:1773–1774

    Article  PubMed  CAS  Google Scholar 

  • Sullivan MJ, Knight JD, Higginbotham MB, Cobb FR (1989) Relation between central and peripheral hemodynamics during exercise in patients with chronic heart failure. Muscle blood flow is reduced with maintenance of arterial perfusion pressure. Circulation 80:769–781

    PubMed  CAS  Google Scholar 

  • Sumimoto T, Sugiura T, Takeuchi M, Yuasa F, Iwasaka T, Inada M (1993) Overshoot in mixed venous oxygen saturation during recovery from supine bicycle exercise in patients with recent myocardial infarction. Chest 103:514–520

    Article  PubMed  CAS  Google Scholar 

  • Taylor JB, Lown B, Polanyi M (1972) In vivo monitoring with a fiber optic catheter. JAMA 221:667–673

    Article  PubMed  CAS  Google Scholar 

  • Waller JL, Kaplan JA, Bauman DI, Craver JM (1982) Clinical evaluation of a new fiberoptic catheter oximeter during cardiac surgery. Anesth Analg 61:676–679

    Article  PubMed  CAS  Google Scholar 

  • Wippermann CF, Huth RG, Schmidt FX, Thul J, Betancor M, Schranz D (1996) Continuous measurement of cardiac output by the Fick principle in infants and children: comparison with the thermodilution method. Intensive Care Med 22:467–471

    Article  PubMed  CAS  Google Scholar 

  • Working Group on Cardiac Rehabilitation and Exercise Physiology, Working Group on Heart Failure of the European Society of Cardiology (2001) Recommendations for exercise testing in chronic heart failure patients. Eur Heart J 22:37–45

    Article  Google Scholar 

Download references

Acknowledgments

This research was supported by grants from Pfizer Pharmaceutical Company, Inc. and from the Research Foundation of the Máxima Medical Centre.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Eindhoven University of Technology, Postbox 513, 5600 MB, Eindhoven, The Netherlands

    Boudewijn T. H. M. Sleutjes & Frans N. van de Vosse

  2. Máxima Medical Centre, Department of Sports Medicine, Postbox 7777, 5500 MB, Veldhoven, The Netherlands

    Hareld M. C. Kemps & Goof Schep

  3. Máxima Medical Centre, Department of Cardiology, Postbox 7777, 5500 MB, Veldhoven, The Netherlands

    Eric J. M. Thijssen

  4. Department of Clinical Physics, Máxima Medical Centre, Postbox 7777, 5500 MB, Veldhoven, The Netherlands

    Chris H. Peters & Pieter F. F. Wijn

  5. Departments of Applied Physics, Eindhoven University of Technology, Postbox 513, 5600 MB, Eindhoven, The Netherlands

    Pieter F. F. Wijn

Authors
  1. Boudewijn T. H. M. Sleutjes
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  2. Hareld M. C. Kemps
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  3. Eric J. M. Thijssen
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  4. Frans N. van de Vosse
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  5. Goof Schep
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  6. Chris H. Peters
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  7. Pieter F. F. Wijn
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Correspondence to Hareld M. C. Kemps.

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Sleutjes, B.T.H.M., Kemps, H.M.C., Thijssen, E.J.M. et al. The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure. Eur J Appl Physiol 102, 493–496 (2008). https://doi.org/10.1007/s00421-007-0597-2

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  • DOI: https://doi.org/10.1007/s00421-007-0597-2

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