Abstract
Physical activity has been shown to favorably affect metabolic risk markers, including blood lipids. The impact of high-energy turnover, without influencing the traditionally used markers of exercise training effects, on blood lipids is still unclear. The aim was to study the effect of high-volume low-intensity physical activity on the blood lipid pattern, with a tight control of diet and energy balance. Eight untrained men [42.5 (12.1) years, body mass index 24.2 (2.8) kg m−2] were tested in two different 6-week protocols. In the sedentary protocol, the subjects were instructed to limit their everyday physical activity. In the activity protocol, a 2-h physical activity bout was performed 5 days week−1 (~40% of VO2max; equivalent of an additional 21 MJ week−1 in energy expenditure). The diet for both protocols comprised ~40 energy percent (E%) fat, ~50 E% carbohydrates (CHO). The polyunsaturated fatty acids to saturated fatty acids ratio of the diet was ~0.12. There were no changes during each 6-week period or differences between the two protocols in body weight, body composition or aerobic capacity. Low-intensity physical activity did not affect lipid parameters substantially, except for a slightly lower Apo-B/Apo-A1 ratio with the activity protocol (P<0.05). Total and low-density lipoprotein cholesterol, as well as Apo-B and Apo-A1, were increased during the beginning of each 6-week period (P<0.05), but returned to basal levels by the sixth week. In conclusion, 6 weeks of high-volume low-intensity physical activity did not affect blood lipids substantially.
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Andersson A, Nalsen C, Tengblad S, Vessby B (2002) Fatty acid composition of skeletal muscle reflects dietary fat composition in humans. Am J Clin Nutr 6:1222–1229
Andersson A, Sjodin A, Olsson R, Vessby B (1998) Effects of physical exercise on phospholipid fatty acid composition in skeletal muscle. Am J Physiol 3(Pt 1):E432–E438
Baguley T (2002) An introduction to sphericity. http://www.-staff.lboro.ac.uk/~hutsb/Spheric.htm.
Becker W, Pearson M (2002) Dietary habits and nutrient intake in Sweden 1997–1998 [Swedish]
Blundell JE, Stubbs RJ, Hughes DA, Whybrow S, King NA (2003) Cross talk between physical activity and appetite control: does physical activity stimulate appetite? Proc Nutr Soc 3:651–661
Criqui MH,Golomb BA (1998) Epidemiologic aspects of lipid abnormalities. Am J Med 1A:48S–57S
Crouse SF, O’Brien BC, Grandjean PW, Lowe RC, Rohack JJ, Green JS, Tolson H (1997) Training intensity, blood lipids, and apolipoproteins in men with high cholesterol. J Appl Physiol 1:270–277
Duncan GE, Perri MG, Theriaque DW, Hutson AD, Eckel RH, Stacpoole PW (2003) Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care 3:557–562
Durstine JL, Grandjean PW, Cox CA, Thompson PD (2002) Lipids, lipoproteins, and exercise. J Cardiopulm Rehabil 6:385–398
FAO/WHO/UNU (1985) Energy and protein requirements. Report of a joint FAO/WHO/UNU expert consultation. World Health Organ Tech Rep Ser 1–206
Gaesser GA,Rich RG (1984) Effects of high- and low-intensity exercise training on aerobic capacity and blood lipids. Med Sci Sports Exerc 3:269–274
Gaziano JM, Hennekens CH, O’Donnell CJ, Breslow JL, Buring JE (1997) Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation 8:2520–2525
Halbert JA, Silagy CA, Finucane P, Withers RT, Hamdorf PA (1999) Exercise training and blood lipids in hyperlipidemic and normolipidemic adults: a meta-analysis of randomized, controlled trials. Eur J Clin Nutr 7:514–522
Havel RJ, Eder HA, Bragdon JH (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34:1345–1353
Hubinger L,Mackinnon LT (1996) The effect of endurance training on lipoprotein(a) [Lp(a)] levels in middle-aged males. Med Sci Sports Exerc 6:757–764
Katzel LI, Bleecker ER, Colman EG, Rogus EM, Sorkin JD, Goldberg AP (1995) Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. A randomized controlled trial. JAMA 24:1915–1921
Kokkinos PF, Holland JC, Narayan P, Colleran JA, Dotson CO, Papademetriou V (1995) Miles run per week and high-density lipoprotein cholesterol levels in healthy, middle-aged men. A dose-response relationship. Arch Intern Med 4:415–420
Kraus WE, Houmard JA, Duscha BD, Knetzger KJ, Wharton MB, McCartney JS, Bales CW, Henes S, Samsa GP, Otvos JD, Kulkarni KR, Slentz CA (2002) Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med 19:1483–1492
Lee IM,Skerrett PJ (2001) Physical activity and all-cause mortality: what is the dose-response relation? Med Sci Sports Exerc 6:S459–S471
Mackinnon LT,Hubinger LM (1999) Effects of exercise on lipoprotein(a). Sports Med 1:11–24
Mensink RP, Zock PL, Kester AD, Katan MB (2003) Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 5:1146–1155
Poobalan A, Aucott L, Smith WC, Avenell A, Jung R, Broom J, Grant AM (2004) Effects of weight loss in overweight/obese individuals and long-term lipid outcomes—a systematic review. Obes Rev 1:43–50
Seigler L,Wu WT (1981) Separation of serum high-density lipoprotein for cholesterol determination: ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride. Clin Chem 6:838–841
Siri WE (1961) Body compostion from fluid spaces and density: analysis of methods. National Academy of Sciences, Washinton DC, pp 223–244
Sunami Y, Motoyama M, Kinoshita F, Mizooka Y, Sueta K, Matsunaga A, Sasaki J, Tanaka H, Shindo M (1999) Effects of low-intensity aerobic training on the high-density lipoprotein cholesterol concentration in healthy elderly subjects. Metabolism 8:984–988
Superko HR (1991) Exercise training, serum lipids, and lipoprotein particles: is there a change threshold? Med Sci Sports Exerc 6:677–685
Tanasescu M, Leitzmann MF, Rimm EB, Willett WC, Stampfer MJ, Hu FB (2002) Exercise type and intensity in relation to coronary heart disease in men. JAMA 16:1994–2000
Thompson PD, Yurgalevitch SM, Flynn MM, Zmuda JM, Spannaus-Martin D, Saritelli A, Bausserman L, Herbert PN (1997) Effect of prolonged exercise training without weight loss on high- density lipoprotein metabolism in overweight men. Metabolism 2:217–223
Thune I, Njolstad I, Lochen ML, Forde OH (1998) Physical activity improves the metabolic risk profiles in men and women: the Tromso Study. Arch Intern Med 15:1633–1640
Walldius G, Jungner I, Holme I, Aastveit AH, Kolar W, Steiner E (2001) High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 9298:2026–2033
Acknowledgements
This study was supported by grants from the Agricultural Research Fund (project# 916108). The authors wish to express their gratitude to Professor Bengt Vessby for commenting on the protocol and manuscript, and the analyses of the fatty acids; to Dr. Agneta Andersson and Jeanette Forslund for preparing the experimental diets; and Dr. Kristen Knutson for linguistic and editorial comments.
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Branth, S., Sjödin, A., Forslund, A. et al. Minor changes in blood lipids after 6 weeks of high-volume low- intensity physical activity with strict energy balance control. Eur J Appl Physiol 96, 315–321 (2006). https://doi.org/10.1007/s00421-005-0096-2
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DOI: https://doi.org/10.1007/s00421-005-0096-2