Suppressive mechanism of gastric motility by whole-body vibration

Abstract

Objective: To investigate the mechanism of gastric motility suppression by exposure to whole-body vibration (WBV). Methods: The gastric motility was evaluated by electrogastrography (EGG) under food intake and autonomic nerve blocking agents in ten healthy volunteers. Sinusoidal vertical vibration with a frequency of 4 Hz (1.0 ms⁻² rms) was given to the subject for 10 min. Results: The amplitude of EGG wave and the power spectrum corresponding to the slow wave component was remarkably decreased by vibration exposure. Food intake enhanced the gastric motility about 2.5-fold in the power spectral density. During and after vibration exposure, the response mode was similar to those at fasting states. Under the influence of anticholinergic (scopolamine) and alpha-adrenergic blocking agents (prazosin), the power spectra were decreased. A further decrease was observed during vibration exposure. A beta-adrenergic blocking agent (propranolol) led to a marked increase in the amplitude of EGG and its power spectrum. With pretreatment by a beta-adrenergic blocking agent, however, vibration exposure reduced both of them. Conclusions: These results suggest that short-term exposure to WBV can suppress the gastric myoelectric activity, the responses on which may be mediating by neurohumoral effects as well as the mechanical effect of WBV.