Abstract
Objective
This study aimed to study the relationship between air pollution and stroke (especially emergency stroke) in different regions and determine which air pollutant is the most significantly associated with stroke.
Methods
The number of patients with emergency stroke, air pollutant data and related meteorological indicators were collected from December 2013 to May 2018 for large comprehensive hospitals in Chongqing. The generalized additive model was used to analyse the relationship between air pollution and emergency stroke.
Results
After analysis and adjusting for meteorological indicators and day-of-the-week effects, in the one-pollutant model, every 10 μg/m3 increase in ozone(O3) was associated with a 2.482% (95% CI 1.044%, 3.919%) change in emergency strokes within lag0. For males, every 10 μg/m3 increase of O3 contributed to a 0.77% percent greater change compared with females. For the group younger than 60 years, we observed a 1.14% increase in risk with every 10 μg/m3 increase in O3. The group with pre-existing hypertension had a 0.26% higher risk than the group with no pre-existing hypertension with every 10 μg/m3 increase in O3. In two-pollutant model, when O3 was combined with a 10 μg/m3 increase of NO2, it increased the most significant risk of emergency stroke by 0.22%.
Conclusion
These findings suggest that short-term exposure to O3 within 0 days is associated with emergency outpatient strokes, and younger people (age < 60 years) males and people with hypertension are more sensitive than older people, females and people without pre-existing hypertension.
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Funding
This work was supported by the National Natural Science Foundation of China (No. 41877518, No. 81571843).
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Caizhi Tang wrote the manuscript and analysed the data. Yu Chen, Liang Gong and Qiaoling Song collected the data. Xingshu Chen, Jifu Qu and Yongjun Luo reviewed the results and provided guidelines for presentation and interpretation. All of the authors have read and approved the final manuscript.
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This study was approved by the Ethics Committee of Third Military Medical University (Army Medical University) and performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standard.
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Tang, C., Chen, Y., Song, Q. et al. Short-term exposure to air pollution and occurrence of emergency stroke in Chongqing, China. Int Arch Occup Environ Health 94, 69–76 (2021). https://doi.org/10.1007/s00420-020-01557-y
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DOI: https://doi.org/10.1007/s00420-020-01557-y