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The effects of industrial noise exposure on lipid peroxidation and antioxidant enzymes among workers

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Abstract

Purpose

The aim of this study was to measure individual exposure to noise and its effect on the levels of lipid peroxidation and enzymatic antioxidant defense.

Methods

In this cross-sectional study, 94 male workers working in a food factory in Shahroud, Iran, were selected as the case group and 112 people were also included as the control group. The level of exposure to noise was measured using a dosimeter and the equivalent level was calculated. The levels of malondialdehyde (MDA), catalase (Cat), superoxide dismutase (SOD), and Total Antioxidant Capacity (TAC) were measured in the serum samples of all participants. Independent t test, one-way ANOVA, and multivariate linear regression were used to analyze the data.

Results

The levels of MDA, Cat, and TAC were significantly higher in staff exposed to noise than in the controls. The starch and warehouse units’ staff were exposed to the highest (99.3 ± 3.23 dB) and lowest (77.1 ± 9.68 dB) mean levels of sound pressure. Based on the linear regression model, noise exposure level was the most important predictor variable for levels of MDA (β = 0.48, CI 95% = 0.04–0.93), Cat (β = 0.43, CI 95% = 0.05–0.83), and TAC (β = 0.11, CI 95% = 0.06–0.16).

Conclusions

Noise exposure increases the production of free radicals. As exposure rate increases, the levels of MDA, Cat, and TAC enzymes increase as well.

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Funding

The work was supported by a grant from Shahroud University of Medical Sciences (Grant number 9795).

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Authors and Affiliations

  1. School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran

    Majid Bagheri Hosseinabadi & Jamal Biganeh

  2. Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran

    Narges Khanjani

  3. Environmental and Occupational Health Research Center, Shahroud University of Medical Sciences, Shahroud, Iran

    Mohammad Hossein Ebrahimi

  4. School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran

    Seyed Reza Mirbadie

Authors
  1. Majid Bagheri Hosseinabadi
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  2. Narges Khanjani
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  3. Mohammad Hossein Ebrahimi
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  4. Seyed Reza Mirbadie
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  5. Jamal Biganeh
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Corresponding author

Correspondence to Majid Bagheri Hosseinabadi.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical standards

This study was conducted according to the Helsinki Declaration and approved by the Shahroud University of Medical Sciences Ethics in Research Committee (IR.SHMU.REC.1397.193).

Informed consent

All participants signed a written informed consent form. In addition, all study objectives were fully explained for the worker and they were assured that their information would be completely confidential. Meanwhile, the participants had the right to leave the study at any stage without facing any problems.

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Cite this article

Bagheri Hosseinabadi, M., Khanjani, N., Ebrahimi, M.H. et al. The effects of industrial noise exposure on lipid peroxidation and antioxidant enzymes among workers. Int Arch Occup Environ Health 92, 1041–1046 (2019). https://doi.org/10.1007/s00420-019-01444-1

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  • DOI: https://doi.org/10.1007/s00420-019-01444-1

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