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Prevalence of self-reported symptoms and consequences related to inhalation of airborne chemicals in a Danish general population

  • Nikolaj Drimer BergEmail author
  • Allan Linneberg
  • Asger Dirksen
  • Jesper Elberling
Original Article

Abstract

Objective

To estimate the prevalence and consequences of self-reported symptoms related to inhalation of airborne chemicals in a Danish general population.

Methods

A random sample of 18–69-year-old individuals (n = 6,000) was drawn from the Danish Civil Registration System. A questionnaire on self-reported symptoms related to inhalation of 11 categories of airborne chemicals was mailed to the population. Respondents who reported symptoms received an additional questionnaire to verify the reported symptoms and to characterise factors related to the initial onset of symptoms.

Results

The response rate to the primary questionnaire was 71%. A total of 1,134 individuals (27%, 95% CI 25–28) reported symptoms related to inhalation of airborne chemicals, 141 individuals (3.3%, 95% CI 2.8–3.9) reported adjustments of social life or occupational conditions due to symptoms, whereas 20 individuals (0.5%, 95% CI 0.3–0.7) had made adjustments of both social life and occupational conditions. Women reported more exposures as annoying than men and had more symptoms related to inhalation of airborne chemicals (P < 0.001). However, sex had no effect on the reporting of adjustments of social life or occupational conditions (P = 0.54).

Conclusion

Symptoms related to inhalation of airborne chemicals were common in this general population, and a minority reported that these symptoms affected social life or occupational conditions. Women as compared to men reported more symptoms but not adjustments of social life or occupational conditions.

Keywords

Epidemiology Population-based Prevalence Multiple chemical sensitivity Idiopathic environmental intolerance 

Notes

Acknowledgements

We thank Susanne Schweitz and Anne Marie Topp who provided valuable secretarial assistance. The study was financially supported by Aage Bangs Foundation and the Asthma and Allergy Association of Copenhagen. The funding sources had no involvement on the work.

References

  1. Altman DG (1991) Comparing groups—categorical data. In: Practical statistics for medical research. Chapman & Hall/CRC, LondonGoogle Scholar
  2. Caress SM, Steinemann AC (2003) A review of a two-phase population study of multiple chemical sensitivities. Environ Health Perspect 111:1490–1497PubMedCrossRefGoogle Scholar
  3. Caress SM, Steinemann AC (2004) A national population study of the prevalence of multiple chemical sensitivity. Arch Environ Health 59:300–305PubMedGoogle Scholar
  4. Caress SM, Steinemann AC (2005) National prevalence of asthma and chemical hypersensitivity: an examination of potential overlap. J Occup Environ Med 47:518–522PubMedCrossRefGoogle Scholar
  5. Carlsson F, Karlson B, Orbaek P, Osterberg K, Ostergren PO (2005) Prevalence of annoyance attributed to electrical equipment and smells in a Swedish population, and relationship with subjective health and daily functioning. Public Health 119:568–577PubMedCrossRefGoogle Scholar
  6. Centre For Epidemiology And Research (2003) The New South Wales adult health survey 2002. N S W Public Health Bull 14(Suppl S-4):1–148Google Scholar
  7. Clayton D, Hills M (1993) Confounding and standardization. In: Statistical models in epidemiology. Oxford University Press, LondonGoogle Scholar
  8. Cullen MR (1987) The worker with multiple chemical sensitivities: an overview. Occup Med 2:655–661PubMedGoogle Scholar
  9. Elberling J, Linneberg A, Dirksen A, Johansen JD, Frolund L, Madsen F, Nielsen NH, Mosbech H (2005) Mucosal symptoms elicited by fragrance products in a population-based sample in relation to atopy and bronchial hyper-reactivity. Clin Exp Allergy 35:75–81PubMedCrossRefGoogle Scholar
  10. Hausteiner C, Bornschein S, Hansen J, Zilker T, Forstl H (2005) Self-reported chemical sensitivity in Germany: a population-based survey. Int J Hyg Environ Health 208:271–278PubMedCrossRefGoogle Scholar
  11. Johansson A, Bramerson A, Millqvist E, Nordin S, Bende M (2005) Prevalence and risk factors for self-reported odour intolerance: the Skovde population-based study. Int Arch Occup Environ Health 78:559–564PubMedCrossRefGoogle Scholar
  12. Kreutzer R, Neutra RR, Lashuay N (1999) Prevalence of people reporting sensitivities to chemicals in a population-based survey. Am J Epidemiol 150:1–12PubMedGoogle Scholar
  13. Lacour M, Zunder T, Schmidtke K, Vaith P, Scheidt C (2005) Multiple chemical sensitivity syndrome (MCS)—suggestions for an extension of the U.S. MCS-case definition. Int J Hyg Environ Health 208:141–151PubMedCrossRefGoogle Scholar
  14. Meggs WJ, Dunn KA, Bloch RM, Goodman PE, Davidoff AL (1996) Prevalence and nature of allergy and chemical sensitivity in a general population. Arch Environ Health 51:275–282PubMedCrossRefGoogle Scholar
  15. Miller CS, Prihoda TJ (1999) The environmental exposure and sensitivity inventory (EESI): a standardized approach for measuring chemical intolerances for research and clinical applications. Toxicol Ind Health 15:370–385PubMedGoogle Scholar
  16. Pekkanen J, Sunyer J, Anto JM, Burney P (2005) Operational definitions of asthma in studies on its aetiology. Eur Respir J 26:28–35PubMedCrossRefGoogle Scholar
  17. Sunyer J, Jarvis D, Pekkanen J, Chinn S, Janson C, Leynaert B, Luczynska C, Garcia-Esteban R, Burney P, Anto JM (2004) Geographic variations in the effect of atopy on asthma in the European Community Respiratory Health Study. J Allergy Clin Immunol 114:1033–1039PubMedCrossRefGoogle Scholar
  18. van Wijk CM, Kolk AM (1997) Sex differences in physical symptoms: the contribution of symptom perception theory. Soc Sci Med 45:231—246PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Nikolaj Drimer Berg
    • 1
    Email author
  • Allan Linneberg
    • 2
  • Asger Dirksen
    • 3
  • Jesper Elberling
    • 1
  1. 1.The Danish Research Centre for Chemical Sensitivities, Gentofte HospitalUniversity of CopenhagenGentofteDenmark
  2. 2.Research Centre for Prevention and Health, Glostrup HospitalUniversity of CopenhagenGlostrupDenmark
  3. 3.Department of Respiratory Medicine Y, Gentofte HospitalUniversity of CopenhagenHellerupDenmark

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