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The effects of long-term occupational exposure to dust from herbs

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Abstract

Introduction: Herbs are a heterogeneous group of many species with several thousand plants, which are used in large quantities in the pharmaceutical and food industries. The aim of the study was to analyse the health effects of long-term occupational exposure to dust from herbs. Methods: A group of 150 people occupationally exposed to dust from herbs, consisting of farmers and workers from herbs processing industry, was examined. As a reference group, 50 urban dwellers not exposed to any kind of organic dust were examined. Examined people were interviewed with the help of the ATS questionnaire compiled by Ferris and by the questionnaire developed in the Institute of Agricultural Medicine in Lublin, Poland for examination of work-related symptoms caused by organic dust. The lung function examination (vital capacity (VC), forced expiratory volume in the first second (FEV1), and FEV1/VC (%) of normal ranges) and allergological tests (skin prick test, precipitin test and inhibition of leukocyte migration (MIF) test) with microbial antigens were conducted. Results: 71.3% (95% CI 64.1–78.6%) of the exposed people reported occurrence of work-related symptoms. A post-shift decrease of spirometric values (VC, VC%) was observed in the exposed group (mean decrease 2.6%, P<0.01). A significant relationship was found between the number of work-related symptoms and decrease of FEV1 values, both before (Spearman correlation coefficient r=−0.21, P<0.05) and after work (r=−0.31, P<0.01). In allergological tests, the frequencies of positive reactions in the exposed group were significantly higher than in the reference group. Precipitins specific to Pantoea agglomerans were found in 30.6% (95% CI 23.2–38.1%) of exposed, compared to 12.0% among unexposed (P=0.01). The frequency of positive results in the migration inhibition test was significantly higher among exposed workers for all antigens tested. Conclusion: Long-term exposure to dust from herbs causes work-related symptoms and decrease of lung function parameters, which, finally, may lead to occupational disease.

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References

  • Akerele O (1993) Summary of WHO guidelines for the assessment of herbal medicines. HerbalGram 28:13–19

    Google Scholar 

  • Benito M, Jorro G, Morales C, Pelaez A, Fernandez A (1996) Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 76:416–418

    PubMed  CAS  Google Scholar 

  • Bowszyc J, Bowszyc J, Pawelec D (1975) Test zahamowania migracji leukocytów w mikrohodowlach z pełnej krwi w ocenie odporności komórkowej w gruźlicy (Test for leukocyte migration inhibition in whole blood microcultures for evaluation of cell immunity in tuberculosis). Gruźlica 43:369–374 (in Polish)

    Google Scholar 

  • Calixto JB (2000) Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 33(2):179–189

    Article  PubMed  CAS  Google Scholar 

  • Dupont WD, Plummer WD (1997) PS power and sample size program available for free on the Internet. Controlled Clin Trials 18:274

    Article  Google Scholar 

  • Dutkiewicz J, Mackiewicz B (2000) Kwestionariusz opracowany w Instytucie Medycyny Wsi w Lublinie dotyczący ekspozycji na pyły organiczne i wywoływanych przez nie objawów (Aneks). (The Questionnaire created in The Institute of Agricultural Medicine for studying exposure to organic dusts and work-related symptoms) In: Dutkiewicz J, Skórska C, Mackiewicz B, Cholewa G (eds) Zapobieganie Chorobom Wywoływanym przez Pyły Organiczne w Rolnictwie i Przemyśle Rolnym. Instytut Medycyny Wsi, Lublin, pp85–88 (in Polish)

  • Dutkiewicz J, Krysińska-Traczyk E, Skórska Cz, Sitkowska J, Prażmo Z, Golec M (2001a) Exposure to airborne microorganisms and endotoxin in herb processing plants. Ann Agric Environ Med 8:201–211

    PubMed  CAS  Google Scholar 

  • Dutkiewicz J, Skórska C, Milanowski J, Mackiewicz B, Krysińska-Traczyk E, Dutkiewicz E, Matuszyk A, Sitkowska J, Golec M (2001b) Response of herb processing workers to work—related airborne allergens. Ann Agric Environ Med 8:275–283

    PubMed  CAS  Google Scholar 

  • Ferris BG (1978) Epidemiology standardization project: II. Recommended respiratory disease questionnaires for use with adults and children in epidemiological research. Am Rev Respir Dis 118:7–53

    PubMed  Google Scholar 

  • Golec M, Skórska C, Mackiewicz B, Dutkiewicz J (2004) Immunologic reactivity to work-related airborne allergens in people occupationally exposed to dust from herbs. Ann Agric Environ Med 11:121–127

    PubMed  Google Scholar 

  • Grammer LC (1999) Occupational allergic alveolitis. Ann Allergy Asthma Immunol 12(83):602–606

    Google Scholar 

  • Gruenwald J (1995) The European phytomedicines market: figures, trends, analysis. HerbalGram 34:60–65

    Google Scholar 

  • Jambor J (2001) Kierunki rozwoju krajowego rynku surowców i przetworów zielarskich (The perspectives of Polish herbal products market). Wiadomości Zielarskie 10:1–7 (in Polish)

  • Lemiere C, Cartier A, Lehrer SB, Malo JR (1996) Occupational asthma caused by aromatic herbs. Allergy 51:647–649

    Article  PubMed  CAS  Google Scholar 

  • Mackiewicz B (1998) Study on exposure of pig farm workers to bioaerosols, immunologic reactivity and health effects. Ann Agric Environ Med 5:169–175

    PubMed  CAS  Google Scholar 

  • Mackiewicz B, Skórska C, Dutkiewicz J, Michnar M, Milanowski J, Prażmo Z, Krysińska-Traczyk E, Cisak E (1999) Allergic alveolitis due to herb dust exposure. Ann Agric Environ Med 6:167–170

    PubMed  CAS  Google Scholar 

  • Milanowski J, Dutkiewicz J, Potoczna H, Kuś L, Urbanowicz B (1998) Allergic alveolitis among agricultural workers in eastern Poland: a study of twenty cases. Ann Agric Environ Med 5:31–43

    PubMed  CAS  Google Scholar 

  • Park HS, Kim MJ, Moon HB (1994) Occupational asthma caused by two herb materials, Dioscorea batatas and Pinellia ternata. Clin Exp Allergy 24:575–581

    Article  PubMed  CAS  Google Scholar 

  • Pepys J, Jenkins PA (1965) Precipitin (F.L.H.) test in farmer’s lung. Thorax 20:21–35

    Article  PubMed  CAS  Google Scholar 

  • doPico GA (1986) Health effects of organic dusts in the farm environment. Report on diseases. Am J Ind Med 10:261–265

    Article  PubMed  CAS  Google Scholar 

  • Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC (1993) Lung volumes and forced ventilatory flows. Report working party standardization of lung function tests European community for steel and coal. Official statement of the European Respiratory Society. Eur Respir J 16:5–40

    CAS  Google Scholar 

  • Robbers JE, Tyler VE (1999) Tyler’s herbs of choice: the therapeutic use of phytomedicinals. Haworth Press, New York

    Google Scholar 

  • Skórska C, Mackiewicz B, Dutkiewicz J, Krysińska-Traczyk E, Milanowski J, Feltovich H, Lange J, Thorne PS (1998) Effects of exposure to grain dust in Polish farmers: work-related symptoms and immunologic response to microbial antigens associated with dust. Ann Agric Environ Med 5:147–153

    PubMed  Google Scholar 

  • Skórska C, Mackiewicz B, Dutkiewicz J (2000) Effects of exposure to flax dust in Polish farmers: work-related symptoms and immunologic response to microbial antigens associated with dust. Ann Agric Environ Med 7:111–118

    PubMed  Google Scholar 

  • Spiewak R, Dutkiewicz J (2002) Occupational airborne and hop dermatitis to hop (Humulus lupulus) with non occupational relapses. Ann Agric Environ Med 9:249–252

    PubMed  Google Scholar 

  • Spiewak R, Dutkiewicz J (2004) A farmer’s occupational airborne contact dermatitis masqueraded by coexisting rosacea: delayed diagnosis and legal acknowledgement. Ann Agric Environ Med 11:329–333

    PubMed  Google Scholar 

  • Spiewak R, Skórska C, Dutkiewicz J (2001) Occupational airborne contact dermatitis caused by thyme dust. Contact Dermatitis 44:235–239

    Article  PubMed  CAS  Google Scholar 

  • Strauss MB (1960) The preparation of allergenic extracts for testing and treatment. In: Prigal SJ (ed) Fundamentals of modern allergy. McGraw-Hill, New York, pp 625–637

    Google Scholar 

  • Subiza J, Subiza JL, Alonso M, Hinojosa M, Garcia R, Jerez M, Subiza E (1990) Allergic conjunctivitis to chamomile tea. Ann Allergy 65:127–132

    PubMed  CAS  Google Scholar 

  • Tan RA, Spector SL (1999) Diagnostic testing in occupational asthma. Ann Allergy Asthma Immunol 83:587–592

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledegments

I thank Dr. Czeslawa Skorska (Lublin, Poland) for performing in vitro tests, and Prof. Jacek Dutkiewicz (Lublin) and Dr. Radoslaw Spiewak (Krakow, Poland) for their critical comments on the manuscript.

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  1. Department of Occupational Biohazards, Institute of Agricultural Medicine, Jaczewskiego 2, 20-950, Lublin, Poland

    Marcin Golec

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  1. Marcin Golec
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Correspondence to Marcin Golec.

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Golec, M. The effects of long-term occupational exposure to dust from herbs. Int Arch Occup Environ Health 79, 169–175 (2006). https://doi.org/10.1007/s00420-005-0041-z

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