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Multifocal fibrosclerosis presenting as Grave’s orbitopathy

Bilateral exophthalmos associated with retroperitoneal and sellar fibrosis

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Abstract 

· Background: Multifocal fibrosclerosis (MF) is a rare disease that may be misdiagnosed as Graves’ orbitopathy. The combination of localisations of MF presented here has not been reported before. · Case report: A 44-year-old man was referred with progressive bilateral exophthalmos. CT of his chest and abdomen revealed an intrathoracic and retroperitoneal peri-aortal soft-tissue process with hydronephrosis. Histological examination of orbital masses showed a fibrous process with low inflammatory activity. Later the sella was found to be involved as well. A diagnosis of MF was made. · Conclusion: MF should be considered in the differential diagnosis of bilateral exophthalmos.

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Received: 4 December 1997 Revised version received: 3 March 1998 Accepted: 20 April 1998

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van der Pol, R., Nieuwenhuis, M. & Mourits, M. Multifocal fibrosclerosis presenting as Grave’s orbitopathy . Graefe's Arch Clin Exp Ophthalmol 237, 256–258 (1999). https://doi.org/10.1007/s004170050227

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  • DOI: https://doi.org/10.1007/s004170050227

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