Abstract ·
Background: This report describes the pathology of a myolipoma which occurred in the eyelid. Myolipoma is a benign hamartomatous tumour in which smooth muscle cells are interspersed with adipocytes. · Patient details: an irregular yellowish tumour (30×25 mm) with ill-defined borders had been present for 50 years in the medial part of the left lower eyelid of a 67-year-old woman. The tumour was excised and studied by conventional histology, immunohistochemistry and transmission electron microscopy. · Results: The tumour was formed by bundles of spindle-shaped cells with cigar-shaped nuclei intermingled with multiloculated clear cells containing small eccentric nuclei. By immunohistochemistry, positive staining of the spindle cells was restricted to smooth muscle actin and desmin; the clear cells were non-reactive with the immunohistochemical panel, but fat was identified within the cytoplasm. The ultrastructural features of the spindle cells were those of a leiomyoma, while the clear cells were classified as adipocytes. · Conclusion: This tumour was considered to originate from the media of blood vessels within the tumour.
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Received: 2 June 1997 Revised version received: 6 October 1997 Accepted: 15 October 1997
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Sharara, N., Lee, W. & Weir, C. Myolipoma of the eyelid. Graefe's Arch Clin Exp Ophthalmol 236, 630–634 (1998). https://doi.org/10.1007/s004170050133
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DOI: https://doi.org/10.1007/s004170050133