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The effect of uneventful cataract surgery on Schlemm’s canal and the trabecular meshwork in cases with pseudoexfoliation

  • Glaucoma
  • Published:
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Abstract

Purpose

To evaluate the effect of uneventful cataract surgery on Schlemm’s canal (SC) and the trabecular meshwork (TM) in cases with pseudoexfoliation (PX).

Methods

In this prospective study, 37 PX and 37 normal eyes, who underwent cataract surgery, were included. The PX group was further divided into two subgroups: PX syndrome (PXS) and PX glaucoma (PXG). Preoperative complete ophthalmologic examination, anterior segment (AS) imaging using a Scheimpflug camera, and measurements of SC length and area and TM thickness and length using AS optical coherence tomography (AS-OCT) were performed in all cases. All measurements were repeated at the first and third months after surgery.

Results

Preoperative intraocular pressure (IOP), AS parameters, SC, and TM values showed no significant differences between the groups (p > 0.05). After surgery, there was a significant increase in AS parameter values and a significant decrease in IOP values in both the PX and control groups (p < 0.05). The nasal and temporal SC area showed a significant increase in the PX group after surgery (p = 0.007, p = 0.003, respectively). In the subgroup analysis, the only significant change in the nasal and temporal SC area was in the PXS group (p = 0.006, p = 0.003, respectively).

Conclusion

Cataract surgery resulted in an increase in the SC area in patients with PXS. This increase may be due to multiple mechanisms including the IOP-lowering effect of cataract removal, change in AS, and removal of intraocular PX material after surgery.

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Authors and Affiliations

  1. Department of Ophthalmology, Haydarpasa Numune Training and Research Hospital, Health Sciences University, Tibbiye Street Nr 23, Uskudar, Istanbul, 34668, Turkey

    Oksan Alpogan, Hatice Tekcan, Serhat Imamoglu, Yucel Ozturk & Ruveyde Bolac

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  1. Oksan Alpogan
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  2. Hatice Tekcan
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  3. Serhat Imamoglu
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  4. Yucel Ozturk
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  5. Ruveyde Bolac
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Correspondence to Oksan Alpogan.

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This article does not any studies with animals performed by any of the authors. All procedures performed in studies involving human participants were in accordance with the ethical standards of the (Ethics Committee of Haydarpasa Numune Training and Research Hospital (HNEAH-KAEK 2022/164) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Alpogan, O., Tekcan, H., Imamoglu, S. et al. The effect of uneventful cataract surgery on Schlemm’s canal and the trabecular meshwork in cases with pseudoexfoliation. Graefes Arch Clin Exp Ophthalmol 262, 1271–1279 (2024). https://doi.org/10.1007/s00417-023-06349-x

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  • DOI: https://doi.org/10.1007/s00417-023-06349-x

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