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Patch endothelial keratoplasty for corneal perforations secondary to ocular surface disease: case series

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Abstract

Background

Corneal perforation is an ophthalmic emergency. The conventional management of corneal perforation can be associated with severe complications especially in patients with ocular surface disease. Endothelial keratoplasty has been suggested as an alternative surgical technique for the management of corneal perforations. We present a case series of nine patients with corneal perforation and ocular surface disease managed with secondary patch endothelial keratoplasty.

Methods

This is a retrospective case series of nine patch endothelial keratoplasties performed between 2016 and 2022 at a quaternary eye hospital in Australia. The surgical technique is similar to conventional endothelial keratoplasty except descemetorhexis was not performed.

Results

A total of 9 cases were treated during the review period. Eight of the nine cases had an improvement in visual acuity. One case failed to achieve corneal tectonic objective.

Conclusion

Patch endothelial keratoplasty is a safe secondary procedure for the management of corneal perforations in patients with ocular surface disease.

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Acknowledgements

Thank you Dr. Amberin Fazal, Dr Chris Hodge, and the New South Wales Tissue Bank for their contributions.

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Authors and Affiliations

  1. Department of Ophthalmology, Cornea Unit, Sydney Eye Hospital, 8 Macquarie Street, Sydney, New South Wales, 2000, Australia

    Javier Lacorzana, Sheng Chiong Hong & Constantinos Petsoglou

  2. Department of Ophthalmology, Glaucoma Unit, Birmingham and Mindland Eye Center, Birmingham, UK

    Javier Lacorzana

  3. New South Wales Tissue Bank, New South Wales Organ and Tissue Donation Service, Sydney, Australia

    Pierre Georges & Constantinos Petsoglou

  4. Specialty of Ophthalmology, Faculty of Medicine, University of Sydney, Sydney, Australia

    Constantinos Petsoglou

Authors
  1. Javier Lacorzana
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  2. Sheng Chiong Hong
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  3. Pierre Georges
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  4. Constantinos Petsoglou
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Corresponding author

Correspondence to Sheng Chiong Hong.

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Ethics approval

Ethics approval (protocol number X03-0098) was provided by the local Human Research Ethics Committee (Sydney Local Health District HREC).

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The authors declare no competing interests.

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Lacorzana, J., Hong, S.C., Georges, P. et al. Patch endothelial keratoplasty for corneal perforations secondary to ocular surface disease: case series. Graefes Arch Clin Exp Ophthalmol 262, 519–526 (2024). https://doi.org/10.1007/s00417-023-06194-y

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  • DOI: https://doi.org/10.1007/s00417-023-06194-y

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