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Tilted disc in eyes with fovea plana

  • Retinal Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To report the association of tilted disc (TD) with fovea plana.

Methods

Monocentric retrospective study of consecutive eyes diagnosed with fovea plana, assessed by spectral-domain optical coherence tomography. Analysis of the medical charts and imaging findings of patients to collect demographics, the visual acuity, and the clinical context. The presence of associated conditions was checked by two independent readers in order to classify fovea plana as isolated or part of other conditions.

Results

Twenty-one patients, 9 men and 12 women, aged 12 to 91 years, were included. Fovea plana was isolated and asymptomatic in 10 (47.6%) patients. In 6 (28.5%) patients, fovea plana was associated with ocular albinism and/or nystagmus. In 6 (28.5%) patients, fovea plana was associated with an obliquity of the optic disc typical of TD, isolated (5 cases), or associated with nystagmus (1 case).

Conclusion

An association between TD and fovea plana had been reported only once in the literature and had been considered likely coincidental. However, this association could be more common than initially reported and suggests a common pathological process in eye development during embryogenesis.

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Funding

The study was supported by the CIL-ASSOC, an association for research and education, in Paris, France.

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Authors and Affiliations

  1. Ophthalmology Center for Imaging and Laser, 11 rue Antoine Bourdelle, 75015, Paris, France

    Sylvia Nghiem-Buffet, Lise Sibilia & Salomon Y. Cohen

  2. Department of Ophthalmology, Intercity Hospital and Paris Est University, 40 Avenue de Verdun, 94010, Creteil, France

    Salomon Y. Cohen

Authors
  1. Sylvia Nghiem-Buffet
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  2. Lise Sibilia
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  3. Salomon Y. Cohen
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Contributions

All authors were responsible for and/or involved in the inclusion of patients/data acquisition, data analysis, data review, and interpretation. All authors reviewed the manuscript and approved the final version for submission.

Corresponding author

Correspondence to Salomon Y. Cohen.

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Ethics approval

All procedures were performed in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its subsequent amendments or comparable ethical standards. Ethics approval was obtained from the medical ethics committee of the Federation France Macula.

Competing interests

The authors declare no competing interests related to the topic. Financial disclosures not related to the topic: SNB: Consulting fees from Abbvie, Bayer, Novartis, and Roche. LD: None. SYC: Consulting fees from Abbvie, Bayer, Novartis, Roche, and Thea.

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Nghiem-Buffet, S., Sibilia, L. & Cohen, S.Y. Tilted disc in eyes with fovea plana. Graefes Arch Clin Exp Ophthalmol 261, 3159–3164 (2023). https://doi.org/10.1007/s00417-023-06161-7

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  • DOI: https://doi.org/10.1007/s00417-023-06161-7

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