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Clinical features of idiopathic epiretinal membrane in children and the factors influencing postoperative visual acuity

  • Pediatrics
  • Published:
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Abstract

Purpose

To describe the characteristics and surgical outcomes of idiopathic epiretinal membrane (iERM) in children and to determine the factors associated with postoperative visual acuity (VA).

Methods

We retrospectively reviewed the medical records of 17 patients with iERM (age, < 18 years) who had undergone ERM surgery from 2009 to 2021. Spectral-domain optical coherence tomography features were documented. The eyes with iERMs involving the fovea were assigned to the localized and diffused groups depending on the morphological description of the membrane. Multiple linear regression analysis was used to explore the factors associated with the final VA.

Results

The mean age was 9.2 ± 3.8 years. The mean follow-up period was 38.9 ± 45.4 months. After surgery, the central foveal thickness and the best-corrected VA (BCVA) improved significantly (all, P < 0.05). Fourteen eyes with iERMs showed involvement of the foveal area (localized group, six eyes; diffused group, eight eyes). There were no significant differences in the preoperative BCVA between the two groups (P = 0.064). However, the final BCVA was better in the diffused group than in the localized group (P = 0.043). Multiple regression analysis indicated that the localized membrane (P = 0.042) and lower preoperative BCVA (P = 0.043) were factors associated with a worse final VA in pediatric iERMs.

Conclusions

Surgical removal of ERM showed a high anatomical and functional success rate in children. In pediatric patients with iERMs involving the fovea, a good VA was more common when the membrane was diffused than when it was localized.

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Funding

This study was supported by National Key Research and Development Program of China, Grant/ Award Number: 2017YFA0104103.

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Authors and Affiliations

  1. Dongcheng District, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Science Key Laboratory, Capital Medical University, No. 1, Dongjiaominxiang, 100730, China

    Xiaohan Yang, Bin Mo, Yanping Yu, Biying Qi, Ke Zhang, Xijin Wu, Xinbo Wang & Wu Liu

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  1. Xiaohan Yang
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  2. Bin Mo
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  3. Yanping Yu
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  7. Xinbo Wang
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  8. Wu Liu
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Corresponding author

Correspondence to Wu Liu.

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Ethical approval

All procedures performed in studies involving human participants were adhered to the Helsinki declaration and its lateral amendments. Approval was granted by the ethical review committee of Beijing Tongren Hospital, Capital Medical University.

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Informed consent was obtained from all individual participants included in this study.

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Yang, X., Mo, B., Yu, Y. et al. Clinical features of idiopathic epiretinal membrane in children and the factors influencing postoperative visual acuity. Graefes Arch Clin Exp Ophthalmol 261, 3651–3657 (2023). https://doi.org/10.1007/s00417-023-06156-4

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  • DOI: https://doi.org/10.1007/s00417-023-06156-4

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