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Effect of the base-out recovery point as the surgical target for acute acquired comitant esotropia



To evaluate the treatment efficacy of the preoperative base-out recovery point as the surgical target angle for acute acquired comitant esotropia.


Prospective study. Twenty-two patients with acute acquired comitant esotropia (AACE) underwent strabismus surgery based on the target angle of the preoperative base-out recovery point. The postoperative deviation, positive fusional vergence, and negative fusional vergence were evaluated and compared with those of 23 normal individuals.


The mean follow-up period was 18.68 ± 19.48 months. At the last follow-up, 19 (86.4%) of 22 subjects had orthophoria, whereas 3 (13.6%) had minimal esophoria. The postoperative angle of deviation was significantly smaller than the preoperative angle of deviation at near (P < 0.001) and distance (P < 0.001). Postoperative sensory fusion was significantly better than preoperative fusion at near (P < 0.001) and distance (P < 0.001). The postoperative stereoacuity improved significantly after the surgery at near (P < 0.001) and distance (P < 0.001). Compared with the controls, the convergence and divergence amplitudes in the AACE patients were similar at distance (P > 0.05) but were still narrower at near (P < 0.001).


Good alignment and binocular balance were obtained with the surgical target angle of the base-out recovery point in AACE.

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This study was supported by the Zhejiang Provincial Natural Science Foundation of China (subject number: LY19H120004) and the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission (subject number: 2019KY110).

Author information




Xinping Yu and Jinmao Chen contributed to the study conception and design. Material preparation, data collection, and analysis were performed by Zhiyue Dai, Fuhao Zheng, Meiping Xu, Jinjing Zhou, Minghui Wan, Huanyun Yu, and Fang Hou. The first draft of the manuscript was written by Zhiyue Dai, and all authors commented on previous versions of the manuscript. All the authors have read and approved the final manuscript.

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Correspondence to Xinping Yu.

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Ethics approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Eye Hospital of Wenzhou Medical University Scientific Ethics Committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. The study was approved by the Bioethics Committee of the Eye Hospital of Wenzhou Medical University. This article does not contain any studies with animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interests.

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Dai, Z., Zheng, F., Xu, M. et al. Effect of the base-out recovery point as the surgical target for acute acquired comitant esotropia. Graefes Arch Clin Exp Ophthalmol (2021).

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  • Acute acquired comitant esotropia
  • Preoperative base-out recovery point
  • Strabismus surgery
  • Binocular vision