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Ex vivo porcine model for eye, eyelid, and orbit movement analysis of 4-mm ferromagnetic foreign bodies in MRI

  • Oculoplastics and Orbit
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

Ferromagnetic foreign bodies (FFB) present during magnetic resonance imaging (MRI) explorations can lead to tissue injury due to movement, especially in and around the eyes. Ferromagnetic foreign bodies located in the intraocular area, eyelids, and orbit are thus prohibited from undergoing MRI. The aim of the study was to analyze movement of 4-mm ferromagnetic foreign bodies in MRI in the eye, eyelid, and orbit using computed tomography (CT) scan.

Method

We developed a porcine model using 12 quarters of fresh porcine heads. Each porcine head included one whole orbit with the ocular globe, orbital fat, muscles, and eyelids. Four-millimeter FFB were implanted in the eye within 2 days post-slaughter, and images were acquired within 5 days post-slaughter. Four-millimeter FFB movement was analyzed after 1.5-Tesla (T) MRI. Four locations were tested: intravitreous, suprachoroidal, intraorbital fat, and intrapalpebral. Movement analysis was assessed using computed tomography (CT) scan.

Results

The intravitreous ferromagnetic ball moved 14.0 ± 8.8 mm (p < 0.01), the suprachoroidal ball moved 16.8 ± 5.4 mm (p < 0.01), the intraorbital fat ball moved 5.8 ± 0.9 mm (p > 0.05), and the intrapalpebral ball moved 2.0 ± 0.4 mm (p > 0.05).

Conclusion

The ex vivo porcine model was able to study FFB movement. The 4-mm ferromagnetic balls moved in intravitreous and in suprachoroidal locations after MRI.

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Acknowledgement

Bellamy Michel, Les Fins Gourmets Rheusois.

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Author notes

  1. M. Ghemame, C. Cathelineau, J.-C. Ferré and F. Mouriaux contributed equally to this work.

Authors and Affiliations

  1. Department of Ophthalmology, Rennes University Hospital, F-35000, Rennes, France

    M. Ghemame & F. Mouriaux

  2. Department of Neuroradiology, Rennes University Hospital, F-35033, Rennes, France

    C. Cathelineau, B. Carsin-Nicol & J.-C. Ferré

  3. CNRS, Inserm, BIOSIT- UMS 3480, US_S 018, F-35000, Rennes, France

    P.-A. Eliat

  4. University of Rennes, Rennes University Hospital, CLCC Eugène Marquis, Inserm, LTSI - UMR 1099, F-35000, Rennes, France

    H. Saint-Jalmes

  5. University of Rennes, Rennes University Hospital, Inria, CNRS, INSERM, IRISA, Empenn ERL U-1228, F-35000, Rennes, France

    J.-C. Ferré

  6. University of Rennes, INSERM, UMR 1241, Nutrition, Métabolismes et Cancer (NuMeCan), Rennes, France

    F. Mouriaux

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  1. M. Ghemame
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Correspondence to M. Ghemame.

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Ghemame, M., Cathelineau, C., Carsin-Nicol, B. et al. Ex vivo porcine model for eye, eyelid, and orbit movement analysis of 4-mm ferromagnetic foreign bodies in MRI. Graefes Arch Clin Exp Ophthalmol 260, 311–318 (2022). https://doi.org/10.1007/s00417-021-05258-1

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  • DOI: https://doi.org/10.1007/s00417-021-05258-1

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