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Evaluation of acquired color vision deficiency in retinal vein occlusion using the Rabin cone contrast test

  • Retinal Disorders
  • Published:
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Abstract

Purpose

To investigate acquired color vision deficiency (CVD) using the Rabin cone contrast test (RCCT) in patients with retinal vein occlusion (RVO).

Methods

We retrospectively evaluated 39 patients with macular edema due to RVO who were treated with intravitreal injections of anti-VEGF agents and demonstrated improvement of best-corrected visual acuity to 20/20 Snellen VA or better. The acquired CVD was evaluated by the RCCT and standard pseudo-isochromatic plates-part 2 (SPP-2).

Results

Mean L, M, and S color contrast test (CCT) scores were significantly lower in RVO eyes than in the fellow eyes (L CCTs, 70.0 ± 13.3 vs. 90.0 ± 8.0, respectively, P < 0.01; M CCTs, 85.0 ± 16.6 vs. 95.0 ± 5.7, respectively, P < 0.01; S CCTs, 80.0 ± 21.5 vs. 95.0 ± 7.1, respectively, P < 0.01). Acquired CVD was diagnosed in 25 eyes of 39 patients by the RCCT and in 15 eyes of 39 patients by SPP-2. The RCCT was performed on two different days in 21 patients. It revealed acquired CVD in 17 eyes on the first day and in 10 eyes on the second day. Acquired CVD was improved in 9 eyes, unchanged in 8 eyes, and worsened in 2 eyes.

Conclusions

The RCCT revealed eyes with RVO had acquired CVD. Acquired CVD caused by RVO can be improved further in some cases even after recovery of vision to 20/20. The RCCT may be able to quantitatively diagnose acquired CVD status.

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Authors and Affiliations

  1. Department of Ophthalmology, Shiga University of Medical Science, Seta-Tsukinowacho, Otsu, Shiga, 520-2192, Japan

    Riko Matsumoto, Yoshitsugu Saishin & Masahito Ohji

Authors
  1. Riko Matsumoto
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  2. Yoshitsugu Saishin
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  3. Masahito Ohji
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Corresponding author

Correspondence to Yoshitsugu Saishin.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional review board of the Shiga University of Medical Science Hospital and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The Institutional Review Board of the hospital approved the study protocol.

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Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interests.

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Matsumoto, R., Saishin, Y. & Ohji, M. Evaluation of acquired color vision deficiency in retinal vein occlusion using the Rabin cone contrast test. Graefes Arch Clin Exp Ophthalmol 259, 2961–2966 (2021). https://doi.org/10.1007/s00417-021-05171-7

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  • DOI: https://doi.org/10.1007/s00417-021-05171-7

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