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Intraocular pressure might play a role in the surgical management of patients with epiretinal membrane

  • Retinal Disorders
  • Published:
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Abstract

Purpose

To investigate the prognostic factors and visual outcomes for patients with epiretinal membrane after pars plana vitrectomy and possible interactions between multiple factors.

Methods

A retrospective chart review of adult patients with epiretinal membrane treated with pars plana vitrectomy performed by a single surgeon between February 1, 2015, and January 31, 2017 was conducted. The surgical procedures included standard 25-gauge vitrectomy with peeling of the epiretinal membrane and internal limiting membrane (ILM). Factors including age, sex, vision, intraocular pressure (IOP), lens status, and baseline optical coherence tomography angiography were analyzed to determine any association with visual outcomes. IOP and lens status were evaluated at every visit point and were used for analysis.

Results

Visual changes after pars plana vitrectomy in patients with epiretinal membrane were significantly associated with time, lens status, baseline ellipsoid zone integrity, baseline vision, baseline parafoveal vessel density of superficial capillary plexus (SPVD), and IOP. Further investigation using Johnson-Neyman analysis revealed that vision improved over time, especially in pseudophakic eyes. High IOP at baseline or during follow-up was identified as a significant factor associated with limited visual improvement.

Conclusion

Our study showed that vision improved over time after vitrectomy for patients with epiretinal membrane. The surgical outcomes are more stable in pseudophakic eyes, and vision improved after cataract extraction in phakic eyes. IOP should be managed and monitored closely to optimize surgical and visual outcomes in patients.

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Authors and Affiliations

  1. Department of Information Technology and Management, Fooyin University, Kaohsiung, Taiwan

    Guan-Chyun Lin

  2. Department of Health-Business Administration, Fooyin University, Kaohsiung, Taiwan

    Huey-Shyan Lin

  3. Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

    Yu-Harn Horng

  4. Department of Ophthalmology, Kaohsiung Medical University Hospital, No.100, Tzyou 1st Rd., Sanmin District, Kaohsiung City, 80756, Taiwan

    Hui-Chen Chu & Shwu-Jiuan Sheu

  5. School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

    Shwu-Jiuan Sheu

Authors
  1. Guan-Chyun Lin
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  2. Huey-Shyan Lin
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  3. Yu-Harn Horng
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  4. Hui-Chen Chu
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  5. Shwu-Jiuan Sheu
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Corresponding author

Correspondence to Shwu-Jiuan Sheu.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Kaohsiung Veterans General hospital and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Since this research was retrospective in design using already existing information, patients’ informed consent was waived.

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Lin, GC., Lin, HS., Horng, YH. et al. Intraocular pressure might play a role in the surgical management of patients with epiretinal membrane. Graefes Arch Clin Exp Ophthalmol 258, 2691–2699 (2020). https://doi.org/10.1007/s00417-020-04870-x

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  • DOI: https://doi.org/10.1007/s00417-020-04870-x

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