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Preoperative central macular thickness as a risk factor for pseudophakic macular edema

  • Retinal Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

This study aims to determine whether elevated central macular thickness (CMT) before uncomplicated cataract surgery may be a risk factor for developing cystic macular edema (CMEs) as measured by Cirrus-OCT and defined as the presence of macular intraretinal cysts.

Methods

A prospective study in Hospital Universitario Poniente, Almeria, Spain, where 379 patients were included for optical coherence tomography (OCT) before cataract surgery, the following day, at 1 month and at 3 months and the presence of macular intraretinal cysts assessed by OCT. Patients with known risk factors for developing CME and patients who developed major surgical complications were excluded.

Results

One hundred seventy-nine patients completed the study. The pre-surgical CMT was 257.75 (20.60) μm measured by Cirrus-OCT. After 1 month, there was an average increase in CMT of 277.86 (45.29) μm, and this increase in thickness decreased after 3 months to an average value of 267.86 (20.17) μm. There were 10.34% of patients with cysts in some of the controls after surgery. This study proposes a binary logistic model to predict the presence of CME depending on the pre-surgery CMT. The cut-off point was 260.5 μm.

Conclusion

Patients with pre-surgical macular thickness > 260.5 μm measured by Cirrus- OCT before cataract surgery, no known risk factors for developing CME and no major surgical complications presented 9.08 times more probability to develop macular intraretinal cysts after uncomplicated cataract surgery.

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Data availability

Castro-Luna, Gracia; Doncel-Fernandez, Carlos (2020), “CATARACT SURGERY”, Mendeley Data, V2, doi: https://doi.org/10.17632/wrv9p63dsp.2

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Acknowledgements

The authors would like to thank Mamen Olvera Lopez (FIBAO) for her assistance with statistical analysis, Irene Villegas (Unit of Investigation Hospital de Poniente) for her assistance with methodology, and the Department of Ophthalmology of Hospital Universitario Poniente for their support.

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Authors and Affiliations

  1. Department of Ophtalmology, Hospital Universitario de Poniente, Almeria, Spain

    C. J. Doncel-Fernández, M. L. Alferez-Asenjo & A. Quereda-Castañeda

  2. Department of Nursery, Physiotherapy and Medicine, University of Almería, Almería, Spain

    G. Castro-Luna

Authors
  1. C. J. Doncel-Fernández
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  2. M. L. Alferez-Asenjo
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  3. A. Quereda-Castañeda
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Contributions

Doncel-Fernandez, CJ has contributed to methodology, research design, writing original draft, writing review and editing, and data acquisition and analysis. Alferez-Asenjo, ML has contributed to methodology, research design, and data acquisition. Quereda-Castañeda, A has contributed to methodology, research design, and data acquisition. Castro-Luna, G has contributed to writing review and editing, and data analysis.

Corresponding author

Correspondence to C. J. Doncel-Fernández.

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Conflict of interest

The authors declare that they have no conflict of interests.

Ethics approval

The study with reference E.C. 21/2017 was approved by the Almeria Research Ethics Committee (CEIC-AL). The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Doncel-Fernández, C.J., Alferez-Asenjo, M.L., Quereda-Castañeda, A. et al. Preoperative central macular thickness as a risk factor for pseudophakic macular edema. Graefes Arch Clin Exp Ophthalmol 259, 37–43 (2021). https://doi.org/10.1007/s00417-020-04862-x

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  • DOI: https://doi.org/10.1007/s00417-020-04862-x

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