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Descemet membrane endothelial keratoplasty (DMEK) early stage graft failure in eyes with preexisting glaucoma

  • Cornea
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Abstract

Purpose

To evaluate the effect of a preexisting glaucoma on the early postoperative outcome of a descemet membrane endothelial keratoplasty (DMEK).

Methods

All patients who underwent DMEK surgery at the Department of Ophthalmology of the University of Muenster with a follow-up of at least 3 months (90d) were included in this study. The best corrected distance visual acuity (BCDVA), the intraocular pressure (IOD), the rate of re-keratoplasty and the rebubbling rate were inter alia recorded. The results of patients with (group 1) and without a preexisting glaucoma (group 2) were compared.

Results

74 eyes of 59 patients with a mean follow-up of 152 ± 70 days were included. 65 eyes were in group 1 and 9 eyes in group 2. The BCDVA significantly improved in both groups after surgery (p < 0.03). The Re-keratoplasty rate (p = 0.172), the number of rebubblings per patient (p = 0.571) and the rebubbling rate (p = 0.939) were not significantly different in patients without glaucoma compared to patients with a preexisting glaucoma.

Conclusions

In the early stage outcome of DMEK no significant impact of a preexisting glaucoma was found.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Muenster Medical Center, Domagkstraße 15, 48149, Muenster, Germany

    Maximilian Treder, Maged Alnawaiseh & Nicole Eter

Authors
  1. Maximilian Treder
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  2. Maged Alnawaiseh
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  3. Nicole Eter
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Corresponding author

Correspondence to Maximilian Treder.

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Funding

No funding was received for this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Financial disclosure

M Treder, Allergan, Novartis; M Alnawaiseh, None; N Eter, Novartis, Bayer, Allergan, Heidelberg Engineering, Bausch and Lomb, Alimera, Roche.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

For this type of study formal consent is not required.

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Treder, M., Alnawaiseh, M. & Eter, N. Descemet membrane endothelial keratoplasty (DMEK) early stage graft failure in eyes with preexisting glaucoma. Graefes Arch Clin Exp Ophthalmol 255, 1417–1421 (2017). https://doi.org/10.1007/s00417-017-3668-z

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  • DOI: https://doi.org/10.1007/s00417-017-3668-z

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