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Descemet stripping automated endothelial keratoplasty using corneas from elderly donors

  • Cornea
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Abstract

Purpose

To evaluate the outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) using corneas from elderly donors.

Methods

A total of 90 eyes that underwent DSAEK at Juntendo University Hospital between January 2008 and December 2012 were divided into two groups. Group 1 was eyes that received corneas from elderly donors aged 80 years or older (29 eyes), and group 2 was eyes that received corneas from donors aged 79 years or younger (61 eyes). Patient characteristics and visual acuity, endothelial cell density, and postoperative complications at 2 years after surgery were examined retrospectively.

Results

The mean age of the donors was 86.3 ± 28.9 years (range, 80–98 years) in group 1 and 62.1 ± 23.2 years (range, 26–79 years) in group 2. At 2 years after surgery, median logMAR visual acuity was 0.48 ± 0.38 in group 1 and 0.42 ± 0.47 in group 2, while the median loss of endothelial cell density was 38.9 ± 22.5 % and 39.7 ± 23.8 %, respectively. There was no significant difference between the two groups for all the parameters.

Conclusions

The rate of endothelial cell loss at 2 years after surgery was similar regardless of donor age (≥80 years vs ≤79 years). It seems reasonable to use corneas from donors aged 80 years or older for DSAEK provided the selection criteria are fulfilled.

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Authors and Affiliations

  1. Department of Ophthalmology, Juntendo University Graduate School of Medicine, 3-1-3 Hongo Bunkyo-ku, Tokyo, Japan, 113-8431

    Satoru Nakatani & Akira Murakami

Authors
  1. Satoru Nakatani
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  2. Akira Murakami
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Correspondence to Satoru Nakatani.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

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No funding was received for this research.

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Nakatani, S., Murakami, A. Descemet stripping automated endothelial keratoplasty using corneas from elderly donors. Graefes Arch Clin Exp Ophthalmol 254, 1135–1140 (2016). https://doi.org/10.1007/s00417-016-3317-y

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  • DOI: https://doi.org/10.1007/s00417-016-3317-y

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