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Spherical aberration reduction in nuclear cataracts

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Abstract

Purpose

To measure higher-order aberrations (HOAs) in nuclear cataracts and to investigate spherical aberration changes with nuclear cataract progression.

Methods

A total of 102 eyes of older subjects (>50 years) were classified based on the nuclear opalescence (NO) grading of the Lens Opacities Classification System III: Group 1 (< NO2, 35), 2 (NO2, 23), 3 (NO3, 23), and 4 (≥ NO 4:21 eyes). Wave front measurements were performed with a Hartmann–Shack aberrometer. To investigate lenticular spherical aberration, HOAs were examined in 28 eyes before and after phacoemulsification, followed by insertion of an aberration-free intraocular lens. The relationship between lens opacity grade and ocular and lenticular spherical aberrations were investigated.

Results

Mean spherical aberrations in groups 1, 2, 3, and 4 were 0.25 ± 0.10, 0.16 ± 0.13, 0.12 ± 0.15, and 0.10 ± 0.20 μm, respectively, and showed a significant difference with nuclear opacity grading (p = 0.001). The spherical aberration showed negative associations with nuclear opacity grading (r = −0.408, p < 0.001). The predominant change in HOAs after phacoemulsification was an increase in spherical aberration, and 86 % of lenticular spherical aberrations were presumed to have negative values. The lenticular spherical aberration was negatively correlated with nuclear opacity severity (r = −0.409, p = 0.031).

Conclusions

Ocular spherical aberration decreases with the progression of nuclear cataracts due to the negative correlation between lenticular spherical aberration and nuclear opacity severity.

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Acknowledgments

We specifically thank Professor Choun-Ki Joo and Dr. Young-Sik Yoo of the Department of Convergence Medical Science, College of Medicine, Catholic University of Korea for their measurements of the higher-order aberrations of intraocular lenses.

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Authors and Affiliations

  1. Department of Ophthalmology, Yonsei University Wonju College of Medicine, 20, Ilsan-ro, Wonju-si, Gangwon-do, 26426, Korea

    Jong-Hyuck Lee, Hun Gu Choo & Sun Woong Kim

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  1. Jong-Hyuck Lee
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  2. Hun Gu Choo
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  3. Sun Woong Kim
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Correspondence to Sun Woong Kim.

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No funding was received for this research.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Lee, JH., Choo, H.G. & Kim, S.W. Spherical aberration reduction in nuclear cataracts. Graefes Arch Clin Exp Ophthalmol 254, 1127–1133 (2016). https://doi.org/10.1007/s00417-016-3316-z

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  • DOI: https://doi.org/10.1007/s00417-016-3316-z

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