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Long-term results of ab externo trabeculotomy for glaucoma secondary to chronic uveitis

  • Inflammatory Disorders
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Abstract

Purpose

To present the long-term results of ab externo trabeculotomy in the management of glaucoma secondary to chronic uveitis.

Methods

In this retrospective single-centre case series, medical records of patients with glaucoma secondary to chronic uveitis, who underwent ab externo trabeculotomy, were evaluated. Two definitions of success were used: intraocular pressure (IOP) 6 ≤ IOP ≤ 21 mmHg (success 1) or 6 ≤ IOP ≤ 21 mmHg and at least 25 % reduction from baseline (success 2). Success was complete when no additional medication was required or qualified when additional medication or cycloablative procedures were required to achieve the specific IOP definition.

Results

Twenty-two eyes of 18 patients were included. After 3 years, median IOP decreased from 27 mmHg [range 17–43 mmHg, mean 27.5 mmHg, 95 % confidence interval of the mean (CI) 24.5–30.5 mmHg] to 15 mmHg (range 9–19 mmHg, mean 14.5 mmHg, CI 13–16.1 mmHg). Complete and qualified success 1 was 23 and 45 % after 3 years, respectively. For success 2, the rates were 23 and 32 %, respectively. Hyphema was the most common complication, which resolved completely within 1 month after surgery without further intervention.

Conclusion

Trabeculotomy ab externo was moderately successful in glaucoma secondary to chronic uveitis after 3 years. No sight-threatening complications were observed during the follow-up period.

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Authors and Affiliations

  1. Centre for Ophthalmology, University of Tuebingen, Schleichstr. 12-16, 72076, Tuebingen, Germany

    Bogomil Voykov, Spyridon Dimopoulos, Martin Alexander Leitritz, Deshka Doycheva & Antony William

Authors
  1. Bogomil Voykov
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  2. Spyridon Dimopoulos
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  3. Martin Alexander Leitritz
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  4. Deshka Doycheva
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  5. Antony William
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Correspondence to Bogomil Voykov.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.

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Informed consent was obtained from all individual participants included in the study.

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Voykov, B., Dimopoulos, S., Leitritz, M.A. et al. Long-term results of ab externo trabeculotomy for glaucoma secondary to chronic uveitis. Graefes Arch Clin Exp Ophthalmol 254, 355–360 (2016). https://doi.org/10.1007/s00417-015-3204-y

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  • DOI: https://doi.org/10.1007/s00417-015-3204-y

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