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25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane for the repair of giant retinal tears

  • Retinal Disorders
  • Published:
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Abstract

Purpose

The purpose of this study was to describe the treatment of giant retinal tears (GRTs) with 25-gauge pars plana vitrectomy (PPV) and medium-term postoperative perfluoro-n-octane (MT-PFO).

Methods

The study was a retrospective interventional case series of consecutive patients with GRTs treated with 25-gauge PPV and postoperative MT-PFO for a period of 2–3 weeks. A second, staged procedure was performed in all patients for PFO removal.

Results

Twenty-three eyes of 22 patients were studied, with a mean follow-up of 33.04 ± 19.74 months. Successful reattachment was achieved in 91.3 % of eyes (21/23) after MT-PFO. Retinal re-detachment occurred in five eyes, which was caused by proliferative vitreoretinopathy. Additional complications included cataract progression (n = 10), foreign body response (30.4 %, 7/23), and transient intraocular pressure (IOP) elevation (8/23, 34.8 %). Transient IOP elevation was associated with worse visual outcome (p = 0.01).

Conclusions

MT-PFO was found to be an effective and safe technique for operative management of GRTs. In the majority of patients, retinas remained attached without further surgical intervention. Cataract progression, intraocular inflammation, and associated increased intraocular pressure are potential complications of MT-PFO.

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Ethical standards

This study conformed to the tenets set forth in the Declaration of Helsinki, and was performed in accordance with the Health Insurance Portability and Accountability Act of 1996 (HIPAA). The study was approved by the institutional review board of the University of Tennessee Health Science Center at Memphis, TN. Patients were included only after providing informed consent for study participation.

Conflict of interest

Dr. Charles is a consultant for Alcon Laboratories, Fort Worth, TX.

All other authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements) or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Author information

Authors and Affiliations

  1. Department of Vitreoretinal Surgery, Charles Retina Institute, 6401 Poplar Avenue, Suite 190, Memphis, TN, 38119, USA

    John C. Randolph, Rocio I. Diaz, Eric J. Sigler, Jorge I. Calzada & Steve Charles

  2. Department of Vitreoretinal Surgery, Center for Retina and Macular Disease, Winter Haven, FL, USA

    John C. Randolph

  3. Division of Medical and Surgical Diseases of the Retina, Vitreous and Macula, Ophthalmic Consultants of Long Island, Lynbrook, NY, USA

    Eric J. Sigler

Authors
  1. John C. Randolph
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  2. Rocio I. Diaz
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  3. Eric J. Sigler
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  4. Jorge I. Calzada
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  5. Steve Charles
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Corresponding author

Correspondence to Rocio I. Diaz.

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Randolph, J.C., Diaz, R.I., Sigler, E.J. et al. 25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane for the repair of giant retinal tears. Graefes Arch Clin Exp Ophthalmol 254, 253–257 (2016). https://doi.org/10.1007/s00417-015-3049-4

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  • DOI: https://doi.org/10.1007/s00417-015-3049-4

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