Abstract
Background
Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage (IHAPSH) is a clinical syndrome most commonly affecting myopic eyes with tilted discs that usually resolves spontaneously without treatment. Subretinal hemorrhage usually occurs peripapillary on the nasally adjacent side near the optic disc. The etiology of this condition is still unknown. The purpose of this study was to determine if a crowded optic nerve head and small scleral canal are involved in the pathogenetic mechanisms of IHAPSH.
Methods
Twelve subjects with IHAPSH diagnosed at the Affiliated Ophthalmology Hospital of the First Clinical College of Harbin Medical University and 24 control subjects were examined. The size of the inner aspect of the scleral canal and level of nerve fiber crowding of the optic nerve head were analyzed with optic nerve head analysis software packet of the Stratus Optical Coherence Tomography software and manual segmentation software. The Mann–Whitney U test and multiple comparisons (with the Bonferroni correction method) were performed. p values less than 0.002 (two-sided) were considered statistically significant. The area, perimeter, and the perimeter/area ratio of the optic disc, vertical and horizontal diameter of the inner aspect of the scleral canal, vertical integrated rim area (VIRA), and the rim area were calculated.
Results
The area and perimeter of the optic disc and the horizontal diameter of the inner aspect of the scleral canal were significantly lower in the affected and contralateral eyes of the subjects with IHAPSH than in the eyes of the controls. Conversely, the IHAPSH-affected and contralateral eyes had significantly higher perimeter/area ratio of the optic disc, VIRA, and rim area values than the control eyes. The VIRA and rim area were greater in the IHAPSH-affected eyes than in the contralateral eyes.
Conclusions
Patients with IHAPSH have smaller optic discs and scleral canals than control subjects, with a higher level of nerve fiber crowding.
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Financial disclosure
This study was supported by the International Science & Technology Cooperation Project of Heilongjiang Province, China (WB08B02), Harbin, China.
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The authors have full control of all primary data and they agree to allow Graefes Archive for Clinical and Experimental Ophthalmology to review their data upon request.
Yan Teng, Xuhui Yu, and Yufei Teng contributed equally to this work.
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Teng, Y., Yu, X., Teng, Y. et al. Evaluation of crowded optic nerve head and small scleral canal in intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage. Graefes Arch Clin Exp Ophthalmol 252, 241–248 (2014). https://doi.org/10.1007/s00417-013-2459-4
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DOI: https://doi.org/10.1007/s00417-013-2459-4