Abstract
Background
To compare postoperative cornea endothelial cell loss between combined phacovitrectomy and pars plana vitrectomy (PPV) with fragmentation.
Methods
Eighty-eight consecutive patients (92 eyes) who underwent combined phacovitrectomy (53 eyes from 50 patients) or PPV with fragmentation (39 eyes from 38 patients) were enrolled in this retrospective study. Endothelial cell density (ECD) was calculated with specular microscopy at 1 and 3 months after surgery.
Results
At 3 months after surgery, the mean ECD decreased significantly from 2,646 ± 296 cells/mm2 to 2,422 ± 347 cells/mm2 in the combined phacovitrectomy group (P < 0.001). However, the PPV with fragmentation group did not show any significant changes in ECD during the same period (from 2,123 ± 628 cells/mm2 to 2,073 ± 574 cells/mm2). The mean endothelial cell loss in the combined phacovitrectomy group (7.9 and 9.5 %) was significantly higher than that in the PPV with fragmentation group (0.7 and 2.4 %) both at 1 and 3 months postoperatively (P = 0.001 and P = 0.001 respectively).
Conclusion
In this study, corneal endothelial cell loss during the early postoperative period was significantly higher after combined phacovitrectomy than after PPV with fragmentation.
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The authors have no financial or proprietary interest in any product, method, or material described herein.
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All the authors have full control of all primary data, and they agree to allow Graefe’s Archive for Clinical and Experimental Ophthalmology to review the data of the current study if requested.
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Eom, Y., Kim, SW., Ahn, J. et al. Comparison of cornea endothelial cell counts after combined phacovitrectomy versus pars plana vitrectomy with fragmentation. Graefes Arch Clin Exp Ophthalmol 251, 2187–2193 (2013). https://doi.org/10.1007/s00417-013-2440-2
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DOI: https://doi.org/10.1007/s00417-013-2440-2