Skip to main content

Advertisement

SpringerLink
Log in

CD44 isoforms in human retinal and choroidal endothelial cells

  • Letter to the Editor
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bajorath J (2000) Molecular organization, structural features, and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions. Proteins 39:103–111

    Article  PubMed  CAS  Google Scholar 

  2. Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI (1992) Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 89:12160–12164

    Article  PubMed  CAS  Google Scholar 

  3. Liu NP, Roberts WL, Hale LP, Levesque MC, Patel DD, Lu CL, Jaffe GJ (1997) Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 38:2027–2737

    PubMed  CAS  Google Scholar 

  4. Xu H, Manivannan A, Jiang HR, Liversidge J, Sharp PF, Forrester JV, Crane IJ (2004) Recruitment of IFN-gamma-producing (Th1-like) cells into the inflamed retina in vivo is preferentially regulated by P-selectin glycoprotein ligand 1:P/E-selectin interactions. J Immunol 172:3215–2324

    PubMed  CAS  Google Scholar 

  5. Mochimaru H, Takahashi E, Tsukamoto N, Miyazaki J, Yaguchi T, Koto T, Kurihara T, Noda K, Ozawa Y, Ishimoto T, Kawakami Y, Tanihara H, Saya H, Ishida S, Tsubota K (2009) Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization. Invest Ophthalmol Vis Sci 50:4410–4415

    Article  PubMed  Google Scholar 

  6. Smith JR, Choi D, Chipps TJ, Pan Y, Zamora DO, Davies MH, Babra B, Powers MR, Planck SR, Rosenbaum JT (2007) Unique gene expression profiles of donor-matched human retinal and choroidal vascular endothelial cells. Invest Ophthalmol Vis Sci 48:2676–2684

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This work was supported by grants from the National Institutes of Health (RO1 EY019875 and R01 EY019042), the International Retina Research Foundation, and Research to Prevent Blindness (unrestricted grant to Casey Eye Institute).

The authors have no financial relationship with the organizations that sponsored the research

Author information

Authors and Affiliations

  1. Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA

    Timothy J. Chipps, Binoy Appukuttan, Yuzhen Pan & Justine R. Smith

  2. Department of Cell and Developmental Biology, Oregon Health & Science University, Portland, OR, USA

    Justine R. Smith

  3. Oregon Health & Science University, Mail Code: L467AD, Biomedical Research Building, 3181 S.W. Sam Jackson Park Rd, Portland, OR, 97239, USA

    Justine R. Smith

Authors
  1. Timothy J. Chipps
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Binoy Appukuttan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yuzhen Pan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Justine R. Smith
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Justine R. Smith.

Additional information

The authors have full control of all primary data, and agree to allow Graefe's Archive for Clinical and Experimental Ophthalmology to review their data upon request.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chipps, T.J., Appukuttan, B., Pan, Y. et al. CD44 isoforms in human retinal and choroidal endothelial cells. Graefes Arch Clin Exp Ophthalmol 251, 1245–1246 (2013). https://doi.org/10.1007/s00417-012-2103-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-012-2103-8

Keywords

Search

Navigation