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Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion

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Abstract

Background

The changes of perifoveal capillary blood flow velocity (BFV), visual acuity, and retinal thickness after pars plana vitrectomy (PPV) have been unclear in patients with branch retinal vein occlusion (BRVO) and macular edema.

Methods

In a prospective study, PPV was performed on six eyes of six consecutive BRVO patients with macular edema (two women and four men; mean age: 66.3 ± 5.0 years). Patients were examined preoperatively and 6 months postoperatively. BFV was measured by fluorescein angiography using a scanning laser ophthalmoscope and the tracing method. Macular thickness was examined by optical coherence tomography. Visual acuity was measured preoperatively and postoperatively, and data were converted to the logarithm of the minimum angle of resolution (logMAR).

Results

In all six treated eyes, the macular thickness decreased significantly compared with before PPV (464 ± 98 μm versus 224 ± 55 μm, P  = 0.0082), mean BFV increased significantly compared with before PPV (1.14 ± 0.14 mm/sec versus 1.46 ± 0.21 mm/sec, P  = 0.0013), and mean logMAR decreased significantly compared with before PPV (0.57 ± 0.34 versus 0.17 ± 0.21, P  = 0.0036).

Conclusions

PPV may improve perifoveal microcirculation and the visual prognosis in BRVO patients with macular edema.

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Authors and Affiliations

  1. Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women’s Medical University, 477-96, Owada-shinden, Yachiyo, Chiba, 276-8524, Japan

    Hidetaka Noma & Hideharu Funatsu

  2. Department of Ophthalmology, Tokyo Women’s Medical University, Tokyo, Japan

    Kumi Sakata & Sadao Hori

  3. Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan

    Tatsuya Mimura

  4. Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women’s Medical University, 477-96, Owada-shinden, Yachiyo, Chiba, 276-8524, Japan

    Hidetaka Noma

Authors
  1. Hidetaka Noma
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  2. Hideharu Funatsu
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  3. Kumi Sakata
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  4. Tatsuya Mimura
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  5. Sadao Hori
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Corresponding author

Correspondence to Hidetaka Noma.

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No conflicting relationship exists for any author.

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Noma, H., Funatsu, H., Sakata, K. et al. Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 248, 443–445 (2010). https://doi.org/10.1007/s00417-009-1250-z

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  • DOI: https://doi.org/10.1007/s00417-009-1250-z

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