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Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab

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Abstract

Purpose

To report a case of familial exudative vitreoretinopathy (FEVR) rapidly resolved by intravitreal injection of bevacizumab.

Methods

A 36-year-old woman complained about floaters and visual field defect. Funduscopic examinations revealed retinal vessel anastomosis located between the equator and ora serrata in both eyes. The right eye was accompanied with slight vitreous hemorrhage. Since the patient declined retinal cryopexy for cosmetic reasons, intravitreal bevacizumab injections (1.25 mg/0.05 ml) were performed in both eyes.

Results

Treatment resulted in the rapid regression and the accelerated fibrosis of neovascular tissues. At 4-month follow-up in the right eye and 1-month follow-up in the left, no signs of systemic or ocular complications were detected.

Conclusions

Intravitreal injection of bevacizumab may be considered as an alternative method in treating FEVR.

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Authors and Affiliations

  1. Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan

    Mizuki Tagami, Sentaro Kusuhara, Shigeru Honda, Yasutomo Tsukahara & Akira Negi

Authors
  1. Mizuki Tagami
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  2. Sentaro Kusuhara
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  3. Shigeru Honda
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  4. Yasutomo Tsukahara
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  5. Akira Negi
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Corresponding author

Correspondence to Shigeru Honda.

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Tagami, M., Kusuhara, S., Honda, S. et al. Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab. Graefes Arch Clin Exp Ophthalmol 246, 1787–1789 (2008). https://doi.org/10.1007/s00417-008-0949-6

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  • DOI: https://doi.org/10.1007/s00417-008-0949-6

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