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Intravitreal bevacizumab as initial treatment for choroidal neovascularization associated with presumed ocular histoplasmosis syndrome

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Abstract

Purpose

To report a case of juxtafoveal choroidal neovascularization in a patient with presumed ocular histoplasmosis syndrome (POHS) who was treated with intravitreal injection of bevacizumab (Avastin) as initial treatment.

Methods

A 23-year-old woman with POHS presented with sudden dimness of vision and metamorphopsia in the right eye. The patient was examined with ophthalmoscopy, fluorescein angiography, and optical coherence tomography (OCT).

Results

Fundus examination, fluorescein angiography, and OCT of the right eye revealed a juxtafoveal choroidal neovascularization. Intravitreal injection of bevacizumab was performed with a postoperative improvement of visual acuity and resolution of the distortion.

Conclusions

This case report describes a case of juxtafoveal choroidal neovascularization associated with POHS that responded remarkably well to intravitreal injection of bevacizumab.

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Authors and Affiliations

  1. Department of Ophthalmology, Hospital Clinic de Barcelona, Universidad de Barcelona, Calle Villarroel 170, 08036, Barcelona, Spain

    Alfredo Adán, Manuel Navarro, Ricardo P. Casaroli-Marano, Santiago Ortiz & Juan José Molina

  2. Instituto de Microcirugía Ocular, Barcelona, Spain

    Alfredo Adán

Authors
  1. Alfredo Adán
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  2. Manuel Navarro
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  3. Ricardo P. Casaroli-Marano
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  4. Santiago Ortiz
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  5. Juan José Molina
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Corresponding author

Correspondence to Alfredo Adán.

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Adán, A., Navarro, M., Casaroli-Marano, R.P. et al. Intravitreal bevacizumab as initial treatment for choroidal neovascularization associated with presumed ocular histoplasmosis syndrome. Graefes Arch Clin Exp Ophthalmol 245, 1873–1875 (2007). https://doi.org/10.1007/s00417-007-0637-y

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  • DOI: https://doi.org/10.1007/s00417-007-0637-y

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