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807C/T polymorphism in platelet glycoprotein Ia gene is not associated with retinal vein occlusion

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References

  1. The Eye Disease Case-Control Study Group (1996) Risk factors for central retinal vein occlusion. Arch Ophthalmol 114:545–554

    Google Scholar 

  2. Staatz WD, Rajpara SM, Wayner EA, Carter WG, Santoro SA (1989) The membrane glycoprotein Ia–IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen. J Cell Biol 108:1917–1924

    Article  PubMed  CAS  Google Scholar 

  3. Kunicki TJ, Orchekowski R, Annis D, Honda Y (1993) Variability of integrin alpha 2 beta 1 activity on human platelets. Blood 82:2693–2703

    PubMed  CAS  Google Scholar 

  4. Kunicki TJ, Kritzik M, Annis DS, Nugent DJ (1997) Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence. Blood 89:1939–1943

    PubMed  CAS  Google Scholar 

  5. Di Paola J, Federici AB, Mannucci PM, Canciani MT, Kritzik M, Kunicki TJ, Nugent D (1999) Low platelet alpha2beta1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system. Blood 93:3578–3582

    PubMed  Google Scholar 

  6. Bray PF (2000) Platelet glycoprotein polymorphisms as risk factors for thrombosis. Curr Opin Hematol 7:284–289

    Article  PubMed  CAS  Google Scholar 

  7. He L, Pappan LK, Grenache DG, Li Z, Tollefsen DM, Santoro SA, Zutter MM (2003) The contributions of the alpha 2 beta 1 integrin to vascular thrombosis in vivo. Blood 102:3652–3657

    Article  PubMed  CAS  Google Scholar 

  8. Dodson PM, Haynes J, Starcznski J, Farmer J, Shigdar S, Fegan G, Johnson RJ, Fegan C (2003) The platelet glycoprotein Ia/IIa gene polymorphism C807T/G873A: a novel risk factor for retinal vein occlusion. Eye 17:772–777

    Article  PubMed  CAS  Google Scholar 

  9. Weger M, Renner W, Steinbrugger I, Cichocki L, Temmel W, Stanger O, El-Shabrawi Y, Lechner H, Schmut O, Haas A (2005) Role of thrombophilic gene polymorphism in branch retinal vein occlusion. Ophtalmology 112(11):1910–1915

    Article  Google Scholar 

  10. Salomon O, Moisseiev J, Vilganski T, Dardik R, Kurtz S, Shpringer E, Steinberg DM, Rosemberg N (2006) Role of five platelet membrane glycoprotein polymorphisms in branch retinal vein occlusion. Blood Coagul Fibrinolysis 17(6):485–488

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Telma Gadelha.

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Gadelha, T., Biancardi, A.L., Forster, M. et al. 807C/T polymorphism in platelet glycoprotein Ia gene is not associated with retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 245, 1739–1740 (2007). https://doi.org/10.1007/s00417-007-0617-2

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  • DOI: https://doi.org/10.1007/s00417-007-0617-2

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