Abstract
Background
Recent comparisons between transpalpebral tonometry using TGDc-01 and Goldmann applanation tonometry were performed in populations with IOPs between 10 and 20 mmHg. The purpose of this study was to evaluate device deviations depending on different IOP levels (range 5–40 mmHg).
Methods
A total of 68 eyes of 68 patients were included and assigned to four IOP levels according to an initial applanation tonometry assessment: level I, <10 mmHg (n=8); level II, 10–19 mmHg (n=20); level III, 20–29 mmHg (n=20); and level IV, ≥30 mmHg (n=20). Two independent and randomized observers performed three replicate measurements per eye—observer 1 using TGDc-01 tonometry, and observer 2 using Goldmann applanation tonometry. Intraindividual deviations between measurement results were investigated concerning clinical relevance by medians and quartiles, concerning statistical significance by pairwise sign tests; p values <0.05 indicate local statistical significance.
Results
In patients with initial IOP ≥20 mmHg, TGDc-01–based tonometry significantly underestimated the IOP as based on Goldmann applanation tonometry (p<0.001). This effect increased with increasing IOP: IOP level III median difference (TGDc-01 − Goldmann) −1.3 mmHg (interquartile range, −2.5, −0.4), IOP level IV median difference −2.7 mmHg (−3.7, −1.0). In patients with initial IOP <10 mmHg, an at least gradual underestimation by TGDc-01 tonometry (p=0.219; median difference, −0.6, −1.6, 0) was observed. A total 18% of patients showed device deviations >±3 mmHg, and even 35% of those patients with initial IOP ≥30 mmHg.
Conclusions
TGDc-01–based tonometry demonstrated an increasing underestimation of IOP with increasing IOP levels when compared with the current standard method of Goldmann applanation tonometry.
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References
Altman DG, Bland JM (1983) Measurement in medicine: the analysis of method comparison studies. Statistician 32:307–317
Amm M, Hedderich J (2003) Transpalpebral tonometry with a digital tonometer in healthy eyes and after penetrating keratoplasty. Ophthalmologe 100[Suppl 1]:S68
Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1(8476):307–310
Doughty MJ, Zaman ML (2000) Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol 44(5):367–408
Frenkel REP, Hong YJ, Shin DH (1988) Comparison of the Tono-Pen to the Goldmann applanation tonometer. Arch Ophthalmol 106:750–753
Goldmann H, Schmidt T (1957) Über Applanationstonometrie. Ophthalmologica 134:221–242
Iester M, Mermoud A, Achache F, Roy S (2001) New TonoPen XL: comparison with the Goldmann tonometer. Eye 15:52–58
Kao SF, Lichter PR, Bergstrom PJ et al (1987) Clinical comparison of the oculab tono-pen to the Goldmann applanation tonometer. Ophthalmology 94:1541–1544
Krummenauer F, Storkebaum K, Dick HB (2003) Graphic representation of data resulting from measurement comparison trials in cataract and refractive surgery. Ophthalmic Surg Lasers Imaging 34:240–244
Lösch A, Scheuerle AE, Mackensen F, Pfirmann M, Bauer A, Martin M, Becker M (2003) Measurements of intraocular pressure using TGDc-01 and applanation tonometry. Ophthalmologe 100[Suppl 1]:S67
Mendelsohn AD, Forster RK, Mendelsohn SL, Dennis JJ, Heideman DG, Levine IK, Parel JM, Di Maio JM (1987) Comparative tonometric measurements of eye bank eyes. Cornea 6(3):219–225
Moses RA (1958) The Goldmann applanation tonometer. Am J Ophthalmol 46:865–869
Moses RA, Liu CH (1968) Repeated applanation tonometry. Am J Ophthalmol 66:89–91
Motolko MA, Feldman F, Hyde M, Hudy D (1982) Sources of variability in the results of applanation tonometry. Can J Ophthalmol 17(3):93–95
Müller A, Lang GE, Kampmeier J (2003) Prospective comparison of the tonometer TGDc-01 with the Goldmann applanation tonometry and the non-contact tonometry PT 100. Ophthalmologe 100[Suppl 1]:S67
Phelps CD, Phelps GK (1976) Measurement of intraocular pressure: a study of its reproducibility. Graefe Arch Clin Exp Ophthalmol 198:39–43
Quigley HA, Langham ME (1975) Comparative intraocular pressure measurements with the pneumotonograph and Goldmann tonometer. Am J Ophthalmol 80:266–273
Rombold F, Thiel M, Neubauer AS, Hirneiß C, Kampik A (2003) Evaluation of the new mobile TGDc-01 tonometer and comparison with the Goldmann applanation tonometry. Ophthalmologe 100[Suppl 1]:S68
Sandner D, Pillunat LE, Kostov S (2003) Measurement of the intraocular pressure with the “Eyelid Tonometer”-TGD c-01 in comparison to applanation and pneumotonometry. Ophthalmologe 100[Suppl 1]:S68
Schmidt T (1960) The clinical application of the Goldmann applanation tonometer. Am J Ophtalmol 49:967–978
Shields MB (1982) The Intraocular pressure. In: Shields MB (ed) A study guide for glaucoma. Williams and Wilkins: Baltimore, pp 56–60, 141–143, 163
Shimmyo M, Ross AJ, Moy A, Mostafavi R (2003) Intraocular pressure, Goldmann applanation tension, corneal thickness, and corneal curvature in Caucasians, Asians, Hispanics and African Americans. Am J Ophthalmol 136:603–613
Smith R (1979) Applanation tonometry without fluorescence (correspondence). Am J Ophthalmol 87:583
Sudesh S, Moseley J, Thompson JR (1993) Accuracy of Goldmann tonometry in clinical practice. Acta Ophthalmologica 71:185–188
Troost R, Vogel A, Beck S, Schwenn O, Grus F, Pfeiffer N (2001) Clinical comparison of two intraocular pressure measurement methods: SmartLens dynamic observing tonography versus Goldmann. Graefe Arch Clin Exp Ophthalmol 239(12):889–892
Vogel A, Beck S, Schwenn O, Grus F, Krummenauer F, Pfeiffer N (2001) Reproduzierbarkeit der Messung von okulärer Pulsamplitude und intraokularem Druck mittels SmartLens. Ophthalmologe 98:944–949
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Troost, A., Specht, K., Krummenauer, F. et al. Deviations between transpalpebral tonometry using TGDc-01 and Goldmann applanation tonometry depending on the IOP level. Graefe's Arch Clin Exp Ophthalmol 243, 853–858 (2005). https://doi.org/10.1007/s00417-005-1142-9
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DOI: https://doi.org/10.1007/s00417-005-1142-9