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Diffuse choroidal haemangioma in Sturge–Weber syndrome treated with photodynamic therapy under general anaesthesia

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Abstract

Purpose

To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment associated with diffuse choroidal haemangioma in Sturge–Weber syndrome.

Methods

An interventional case report of a 12-year-old girl with Sturge–Weber syndrome who developed an exudative retinal detachment (visual acuity 20/400) that was treated with PDT under general anaesthesia. PDT was performed according to the standard (macular degeneration) protocol, using three nonoverlapping spots of 4,000 μm.

Results

Subretinal fluid resolved completely over a period of 5 months and visual acuity increased to 20/50. No side effects of the PDT treatment were encountered during 9 months’ follow-up.

Conclusion

In our patient PDT with verteporfin effectively resolved the exudative retinal detachment associated with a diffuse choroidal haemangioma. Resolution of subretinal fluid occurred over several months without retreatment. We noted no side effects of the combination PDT and general anaesthesia, nor did we encounter ocular side effects of the treatment.

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References

  1. Anand R (2003) Photodynamic therapy for diffuse choroidal haemangioma associated with Sturge Weber syndrome. Am J Ophthalmol 136:758–760

    Google Scholar 

  2. Anand R, Augsburger JJ, Shields JA (1989) Circumscribed choroidal hemangiomas. Arch Ophthalmol 1107:1338–1342

    Google Scholar 

  3. Bains HS, Cirino AC, Ticho BH, Jampol LM (2004) Photodynamic therapy using verteporfin for a diffuse choroidal haemangioma in Sturge–Weber syndrome. Retina 24:152–155

    Google Scholar 

  4. Farah ME, Costa RA, Muccioli C, Guia TA, Belfort R Jr (2002) Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization in Vogt–Koyanagi–Harada syndrome. Am J Ophthalmol 134:137–139

    Google Scholar 

  5. Ferry AP (2001) Other phakomatoses. In: Schachat AP (ed) Retina, vol 1, 3rd edn. St. Louis, Mosby, pp 596–600

    Google Scholar 

  6. Fuchs AV, Mueller AJ, Grueterich M, Ulbig MW (2002) Transpupillary thermotherapy (TTT) in circumscribed choroidal hemangioma. Graefes Arch Clin Exp Ophthalmol 240:7–11

    Google Scholar 

  7. García-Arumí J, Ramsay LS, Guraya BC (2000) Transpupillary thermotherapy for circumscribed choroidal hemangiomas. Ophthalmology 107:351–357

    Article  CAS  PubMed  Google Scholar 

  8. Gragoudas ES, Li W, Lane AM, Munzenrider J, Egan KM (1999) Risk factors for radiation maculopathy and papillopathy after ocular irradiation. Ophthalmology 106:1571–1578

    Google Scholar 

  9. Postelmans L, Pasteels B, Coquelet P, El Ouardighi H, Verougstraete C, Schmidt-Erfurth U (2004) Severe pigment epithelial alterations in the treatment area following photodynamic therapy for classic choroidal neovascularization in young females. Am J Ophthalmol 138:803–808

    Google Scholar 

  10. Singh AD, Rundle PA, Vardy SJ, Rennie IG (2004) Photodynamic therapy of choroidal haemangioma associated with Sturge–Weber syndrome. Eye DOI:10.1038/sj.eye.6701474

    Google Scholar 

  11. Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group (1999) Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials—TAP Report. Arch Ophthalmol 117:1329–1345

    Google Scholar 

  12. Zografos L, Egger E, Bercher L, Chamot L, Munkel G (1998) Proton beam irradiation of choroidal hemangiomas. Am J Ophthalmol 126:261–268

    Google Scholar 

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Correspondence to R. P. H. M. Müskens.

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Huiskamp, E.A., Müskens, R.P.H.M., Ballast, A. et al. Diffuse choroidal haemangioma in Sturge–Weber syndrome treated with photodynamic therapy under general anaesthesia. Graefe's Arch Clin Exp Ophthalmol 243, 727–730 (2005). https://doi.org/10.1007/s00417-004-1102-9

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  • DOI: https://doi.org/10.1007/s00417-004-1102-9

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