Abstract
Purpose
To report the case of a patient with nodular scleritis who was diagnosed as having sarcoidosis by a biopsy of scleral nodules.
Methods
Case report.
Results
A 26-year-old man with nodular scleritis underwent a biopsy of scleral nodules. The year before, he had been diagnosed with granulomatous iridocyclitis of the right eye. Although sarcoidosis had been suspected, extensive systemic examinations resulted in no positive findings of sarcoidosis. Histopathological specimens revealed non-caseating epithelioid granuloma with giant cells. The nodular scleritis was resolved by topical corticosteroids.
Conclusions
A scleral biopsy is useful for the diagnosis of sarcoidosis when the patient has nodular scleritis with no systemic signs.
References
Belfer MH, Stevens RW (1998) Sarcoidosis: a primary care review. Am Fam Physician 58:2041–2050
Heiligenhaus A, Michel D, Koch JM (2003) Nodular scleritis in a patient with sarcoidosis. Br J Ophthalmol 87:507–508
Jabs DA, Johns CJ (1986) Ocular involvement in chronic sarcoidosis. Am J Ophthalmol 102:297–301
Newman LS, Rose CS, Maier LA (1997) Sarcoidosis. N Engl J Med 33:1224–1234
Rothova A (2000) Ocular involvement in sarcoidosis. Br J Ophthalmol 84:110–116
Spaide RF, Ward DL (1990) Conjunctival biopsy in the diagnosis of sarcoidosis. Br J Ophthalmol 74:469–471
Tuft SJ, Watson PG (1991) Progression of scleral disease. Ophthalmology 98:467–471
Usui Y, Kaiser ED, See RF, Rao NA, Sharma OP (2002) Update of ocular manifestations in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 19:167–175
Watson PG, Hayreh SS (1976) Scleritis and episcleritis. Br J Ophthalmol 60:163–191
Weinreb RN (1984) Diagnosing sarcoidosis by transconjunctival biopsy of the lacrimal gland. Am J Ophthalmol 97:573–576
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Saito, W., Kotake, S. & Ohno, S. A patient with sarcoidosis diagnosed by a biopsy of scleral nodules. Graefe's Arch Clin Exp Ophthalmol 243, 374–376 (2005). https://doi.org/10.1007/s00417-004-1023-7
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DOI: https://doi.org/10.1007/s00417-004-1023-7