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Physical and cytological characters of carbon, titanium surface modified intraocular lens in rabbit eyes

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  • Published:
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Abstract

Purpose

To evaluate the physical and cytological characters of carbon (C), titanium (T) surface-modified intraocular lenses (IOLs) in rabbit eyes.

Methods

Water contact angle in air of C, T-IOLs was measured by goniometer using the sessile drop method. Extracapsular cataract extraction (ECCE) and IOL implantation were performed in rabbit eyes. Cells adhering to IOLs were measured using the MIAS-2000 Computer Analyzer System at 12 months after operation. The diopters and resolution of C, T-IOLs were measured after 1 year of implantation.

Results

Water contact angle in air of C, T-IOLs (80, 84.5 deg) were significant lower than that of PMMA-IOL (74.8 deg). C, T-IOLs became hydrophobic compared with PMMA-IOLs. C, T-IOLs did not change significantly in diopters and resolution after 1 year of implantation in rabbit eyes. There were fibroblasts, epitheloid cells, giant cells, lymphocyte cells and fibrous membrane attached to the surface of IOLs.

Conclusions

The optical characteristics of C, T-IOL) were stable in rabbit eyes after 1 year of implantation. The C, T-IOLs became hydrophobic compared with PMMA-IOLs. They also induced foreign body reactions similar to those seen with PMMA-IOLs in rabbit eyes.

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Acknowledgements

The author thanks Prof. Hanqing Gu of Tianjin Medical University for providing IOLs and is grateful to Prof. Jiaqin Yuan for advice.

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Authors and Affiliations

  1. College of Optometry, State University of New York, 33 West 42nd Street, New York, NY 10036, USA

    Zhaoxu Yuan

  2. Tianjin Medical University, 300070, Tianjin , P.R. China

    Zhaoxu Yuan

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  1. Zhaoxu Yuan
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Correspondence to Zhaoxu Yuan.

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The author has no financial or proprietary interest in any materials or method mentioned. No meeting presentation or financial support. No conflict of interest

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Yuan, Z. Physical and cytological characters of carbon, titanium surface modified intraocular lens in rabbit eyes. Graefe's Arch Clin Exp Ophthalmol 241, 840–844 (2003). https://doi.org/10.1007/s00417-003-0728-3

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  • DOI: https://doi.org/10.1007/s00417-003-0728-3

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