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Deep brain stimulation for patients with dystonia in Machado–Joseph disease: three case reports

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Data availability statement

The data that support the findings of this study are available from the corresponding author, [RO], upon reasonable request. The data are not publicly available due to [restrictions e.g. their containing information that could compromise the privacy of research participants].

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Acknowledgements

We are very grateful to Dr. Makoto Taniguchi. He treated our three patients as the head of the Department of Neurosurgery at the Tokyo Metropolitan Neurological Hospital. Unfortunately, he passed away in 2020. We are also very grateful to the staff of the Neurology and Neurosurgery Departments of the Tokyo Metropolitan Neurological Hospital who helped us in our practice (especially Akihiro Yugeta, Takao Shichi, Katsunari Watanabe, and Takashi Kawasaki).

Funding

No specific funding was received for this work.

Author information

Authors and Affiliations

  1. Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu-Shi, Tokyo, 183-0042, Japan

    Jun Ikezawa, Fusako Yokochi, Ryoichi Okiyama, Yoko Sunami & Kazushi Takahashi

  2. Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan

    Ayako Isoo, Takashi Agari & Tohru Terao

  3. Department of Neurosurgery, Atsugi City Hospital, Kanagawa, Japan

    Tohru Terao

Authors
  1. Jun Ikezawa
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  2. Fusako Yokochi
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  3. Ryoichi Okiyama
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  4. Ayako Isoo
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  5. Takashi Agari
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  6. Yoko Sunami
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  7. Tohru Terao
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  8. Kazushi Takahashi
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Contributions

Conception: JI, organization: JI, FY, RO, AI, TA, YS, TT, and KT. execution: JI, FY, RO, AI, TA, YS, TT, and KT. Writing of the first draft: JI, review, and critique: JI, FY, RO, AI, TA, YS, TT, and KT.

Corresponding author

Correspondence to Ryoichi Okiyama.

Ethics declarations

Conflict of interest

The authors declare no conflicts of interest associated with this manuscript. Unrelated to this work, Fusako Yokochi received grants from InSightec, Ltd., for a trial on focused ultrasound for Parkinson’s disease.

Ethical approval

The authors confirm that approval from an institutional review board was not required for this study. We also confirm that the patients provided written informed consent for the publication of their videos. In addition, we confirm that we have read the journal’s position on issues involved in ethical publication and affirm that this work is consistent with those guidelines.

Supplementary Information

Below is the link to the electronic supplementary material.

The video shows a 29-year-old male patient with MJD with dystonia (Case 3). Painful dystonia was pronounced in both the upper and lower extremities before surgery. The patient was able to stand with assistance following surgery, with improvement in the apex foot position. Supplementary file1 (MP4 42990 KB)

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Ikezawa, J., Yokochi, F., Okiyama, R. et al. Deep brain stimulation for patients with dystonia in Machado–Joseph disease: three case reports. J Neurol 270, 3261–3265 (2023). https://doi.org/10.1007/s00415-023-11627-z

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  • DOI: https://doi.org/10.1007/s00415-023-11627-z

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