Skip to main content

Advertisement

SpringerLink
Log in

Baroreflex failure as a long-term sequela of head and neck irradiation

  • Letter to the Editors
  • Published:
Journal of Neurology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Kao J, Lavaf A, Teng MS, Huang D, Genden EM (2008) Adjuvant radiotherapy and survival for patients with node-positive head and neck cancer: an analysis by primary site and nodal stage. Int J Radiat Oncol Biol Phys 71(2):362–370. https://doi.org/10.1016/j.ijrobp.2007.09.058

    Article  PubMed  Google Scholar 

  2. Master S, Koshy N, Wilkinson B, Rosen L, Mills G, Mansour R, Shi R (2017) Effect of radiation therapy on survival in Hodgkin’s lymphoma: a SEER data analysis. Anticancer Res 37(6):3035–3043. https://doi.org/10.21873/anticanres.11658

    Article  CAS  PubMed  Google Scholar 

  3. Sharabi Y, Dendi R, Holmes C, Goldstein DS (2003) Baroreflex failure as a late sequela of neck irradiation. Hypertension 42(1):110–116. https://doi.org/10.1161/01.HYP.0000077441.45309.08

    Article  CAS  PubMed  Google Scholar 

  4. Lohmeier TE, Iliescu R (2015) The baroreflex as a long-term controller of arterial pressure. Physiology (Bethesda) 30(2):148–158. https://doi.org/10.1152/physiol.00035.2014

    Article  CAS  PubMed  Google Scholar 

  5. Shah-Becker S, Pennok M, Sinoway L, Goldenberg D, Goyal N (2017) Baroreceptor reflex failure: review of the literature and potential impact on patients with head and neck cancer. Head Neck 39(2):2135–2141. https://doi.org/10.1002/hed.24857

    Article  PubMed  Google Scholar 

  6. Robertson D, Hollister AS, Biaggioni I, Netterville JL, Mosqueda-Garcia R, Robertson RM (1993) The diagnosis and treatment of baroreflex failure. N Engl J Med 329(20):1449–1455. https://doi.org/10.1056/NEJM199311113292003

    Article  CAS  PubMed  Google Scholar 

  7. Lamotte G, Coon EA, Suarez MA, Sandroni P, Benarroch EE et al (2021) Natural history of afferent baroreflex failure in adults. Neurology 97:e136-144

    Article  PubMed  PubMed Central  Google Scholar 

  8. Freeman R, Chapleau MW (2013) Testing the autonomic nervous system. Handb Clin Neurobiol 115:115–136. https://doi.org/10.1016/B978-0-444-52902-2.00007-2

    Article  Google Scholar 

  9. Lamotte G, Coon EA, Suarex MD, Sandroni P, Benarroch E, Cutsforth-Gregory JK, Mauremann ML, Berini SE, Shouman K, Sletten D, Goodman BP, Low PA, Singer W (2022) Standardised autonomic testing in patients with probable radiation-induced afferent baroreceptor failure. Hypertension 79:50–56. https://doi.org/10.1161/hypertensionaha.121.17805

    Article  CAS  PubMed  Google Scholar 

  10. Goyal M, Shukla P, Gupta D, Bisht S, Verma NS et al (2017) Cardiovascular sequela of neck irradiation in head and neck cancer patients. Int J Rad Biol 93(7):711–716. https://doi.org/10.1080/09553002.2017.1303217

    Article  CAS  PubMed  Google Scholar 

  11. Singer W, Spies JM, McArthur J, Low J, Griffin JW, Nickander KK, Goron V, Low PA (2004) Prospective evaluation of somatic and autonomic small fibers in selected autonomic neuropathies. Neurology 62:612–618

    Article  CAS  PubMed  Google Scholar 

  12. Huang CC, Huang TL, Hsu HC, Chen HC, Lin HC, Chien CY, Fang FM, Chang HW, Tsai NW, Chang WN, Chen SF, Lin TK, Tan TY, Chang CR, Wang HC, Lin WC, Lu CH (2013) Long-term effects of neck irradiation on cardiovascular autonomic function: a study in nasopharyngeal carcinoma patients after radiotherapy. Muscle Nerve 47(3):344–350. https://doi.org/10.1002/mus.23530

    Article  PubMed  Google Scholar 

  13. Shibao C, Okamoto L, Biaggioni I (2012) Pharmacotherapy of autonomic failure. Pharmacol Ther 134(3):279–286. https://doi.org/10.1016/j.pharmthera.2011.05.009

    Article  CAS  PubMed  Google Scholar 

  14. van Lieshout JJ, ten Harkel AD, Wieling W (2000) Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure. Clin Auton Res 10:35–42. https://doi.org/10.1007/BF02291388

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia

    A. J. Clarke, G. Swart, G. M. Halmagyi & J. Spies

  2. Faculty of Medicine and Health, University of Sydney, Sydney, Australia

    A. J. Clarke, C. Milross, G. M. Halmagyi & J. Spies

  3. Department of Head and Neck Surgery, Royal Prince Alfred Hospital, Sydney, Australia

    A. R. Clifford

  4. Department of Radiation Oncology, Chris O’Brien Lifehouse, Sydney, Australia

    C. Milross

Authors
  1. A. J. Clarke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Swart
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. R. Clifford
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. C. Milross
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. M. Halmagyi
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Spies
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. J. Clarke.

Ethics declarations

Conflicts of interest

There are no competing interests to disclose.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Clarke, A.J., Swart, G., Clifford, A.R. et al. Baroreflex failure as a long-term sequela of head and neck irradiation. J Neurol 270, 2784–2788 (2023). https://doi.org/10.1007/s00415-022-11552-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-022-11552-7

Search

Navigation